Tert-butyl 4-(4-chlorobenzyl)piperazine-1-carboxylate

Base Information

Chemical Name:Tert-butyl 4-(4-chlorobenzyl)piperazine-1-carboxylate
CAS No.:77290-30-3
Molecular Formula:C16H23ClN2O2
Molecular Weight:310.824
Hs Code.:2933599090
DSSTox Substance ID:DTXSID20589908
Wikidata:Q82483547
Mol file:77290-30-3.mol

Synonyms:77290-30-3;TERT-BUTYL 4-(4-CHLOROBENZYL)PIPERAZINE-1-CARBOXYLATE;tert-butyl 4-[(4-chlorophenyl)methyl]piperazine-1-carboxylate;SCHEMBL5536182;DTXSID20589908;WKCMDNWDUUGHQM-UHFFFAOYSA-N;MFCD09953051;AKOS027439706;DA-02898;D87227;t-Butyl 4-[(4-chlorophenyl)methyl]piperaZine-1-carboxylate

Suppliers and Price of Tert-butyl 4-(4-chlorobenzyl)piperazine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TERT-BUTYL-4-(4-CHLOROBENZYL)PIPERAZINE-1-CARBOXYLATE 95.00%
5MG
$ 497.24

Total 4 raw suppliers

Chemical Property of Tert-butyl 4-(4-chlorobenzyl)piperazine-1-carboxylate

Chemical Property:

Boiling Point:388.5±37.0 °C(Predicted)
PKA:6.11±0.10(Predicted)
PSA：32.78000
Density:1.168±0.06 g/cm3(Predicted)
LogP:3.26850
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:310.1448057
Heavy Atom Count:21
Complexity:341

Purity/Quality:

99% ^*data from raw suppliers

TERT-BUTYL-4-(4-CHLOROBENZYL)PIPERAZINE-1-CARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCN(CC1)CC2=CC=C(C=C2)Cl

Technology Process of Tert-butyl 4-(4-chlorobenzyl)piperazine-1-carboxylate

There total 4 articles about Tert-butyl 4-(4-chlorobenzyl)piperazine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 104-83-6
1-Chloro-4-(chloromethyl)benzene

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 77290-30-3
tert-butyl 4-(4-chlorobenzyl)piperazine-1-carboxylate

Guidance literature:: With potassium carbonate; In ethanol;

Reference yield:

: 104-88-1
4-chlorobenzaldehyde

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 77290-30-3
tert-butyl 4-(4-chlorobenzyl)piperazine-1-carboxylate

Guidance literature:: With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 20 ℃; for 6h; Inert atmosphere;
DOI:10.1016/j.bmc.2013.12.050