AKOS B019364

Base Information

• Chemical Name: AKOS B019364
• CAS No.: 257610-91-6
• Molecular Formula: C13H15NO2S2
• Molecular Weight: 281.39
• Hs Code.: 2934999090
• Mol file: 257610-91-6.mol

Synonyms:ART-CHEM-BB B019364;AKOS B019364;Ethyl 2-isothiocyanato-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate;2-isothiocyanato-5,6,7,8-tetrahydro-4H-cyclohepta[d]thiophene-3-carboxylic acid ethyl ester;ethyl 2-isothiocyanato-5,6,7,8-tetrahydro-4H-cyclohepta[d]thiophene-3-carboxylate;IVK/1269160;Oprea1_179728

Chemical Property of AKOS B019364

Chemical Property:

• PSA: 98.99000
• LogP: 3.92800

Purity/Quality:

98%min ^*data from raw suppliers

Ethyl 2-isothiocyanato-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of AKOS B019364

There total 1 articles about AKOS B019364 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid ethyl ester (40106-13-6) + thiophosgene (463-71-8) → ethyl 2-(isothiocyanato)-5,6,7,8-tetrahydro-4H-cyclohepta[4,5]thiophene-3-carboxylate (257610-91-6)

Guidance literature:

With calcium carbonate; In dichloromethane; water; at 0 ℃; for 3h;

DOI:10.1021/jm991108w

upstream raw materials:

2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid ethyl ester

thiophosgene