BMS 791325

Base Information

Chemical Name:BMS 791325
CAS No.:958002-33-0
Molecular Formula:C36H45N5O5S
Molecular Weight:659.85
Hs Code.:
Mol file:958002-33-0.mol

Synonyms:Beclabuvir

Suppliers and Price of BMS 791325

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
Beclabuvir 99.91%
50mg
$ 1920.00

ChemScene
Beclabuvir 99.91%
10mg
$ 660.00

ChemScene
Beclabuvir 99.91%
5mg
$ 420.00

ChemScene
Beclabuvir 99.91%
1mg
$ 168.00

Total 7 raw suppliers

Chemical Property of BMS 791325

Chemical Property:

PKA:4.44±0.40(Predicted)
PSA：112.57000
Density:1.45±0.1 g/cm3(Predicted)
LogP:6.04060

Purity/Quality:

97% ^*data from raw suppliers

Beclabuvir 99.91% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description Beclabuvir is a non-nucleoside, nonstructural protein 5B (NS5B) polymerase inhibitor approved in Japan as part of a fixed-dose combination product for the treatment of hepatitis C virus (HCV). Upon administration and after intracellular uptake, the drug binds to the allosteric, noncatalytic “Thumb 1” site of NS5B resulting in a decreased rate of viral RNA synthesis and replication.4 Beclabuvir is combined with asunaprevir and declatasvir (both approved in 2014) and was discovered and developed by Bristol-Myers Squibb.

Technology Process of BMS 791325

There total 1 articles about BMS 791325 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 928843-71-4
(1aR,12bS)-8-cyclohexyl-5-[[[(dimethylamino)sulfonyl]amino]carbonyl]-1,12b-dihydro-11-methoxycycloprop[d]indolo[2,1-a][2]benzazepine-1a(2H)-carboxylic acid

: 52407-92-8
3-methyl-3,8-diazabicyclo[3.2.1]octane dihydrochloride

: 958002-33-0
(1aR,12bS)-8-cyclohexyl-N-[(dimethylamino)sulfonyl]-1,1a,2,12b-tetrahydro-11-methoxy-1a-[(3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl]-cycloprop[d]indolo[2,1-a][2]benzazepine-5-carboxamide

Guidance literature:: With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20 ℃; for 0.75h;