Technology Process of 6,6-Dimethyl-tetrahydro-pyran-3-carbaldehyde
There total 5 articles about 6,6-Dimethyl-tetrahydro-pyran-3-carbaldehyde which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
Dess-Martin periodane;
In
dichloromethane;
at 0 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene[2-(iso-propoxy)-5-(N,N-dimethylaminosulfonyl)phenyl]methylene ruthenium(II) dichloride / dichloromethane / 16 h / 50 °C / Inert atmosphere
2.1: hydrogen; palladium on activated charcoal / methanol / 15 h / 30 °C / 1034.32 Torr
3.1: water; lithium hydroxide monohydrate / methanol / 2 h / 20 °C
3.2: pH Ca.3
4.1: dimethylsulfide borane complex / tetrahydrofuran / 16 h / 0 - 30 °C
5.1: Dess-Martin periodane / dichloromethane / 2 h / 0 °C
With
lithium hydroxide monohydrate; 1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene[2-(iso-propoxy)-5-(N,N-dimethylaminosulfonyl)phenyl]methylene ruthenium(II) dichloride; dimethylsulfide borane complex; palladium on activated charcoal; water; hydrogen; Dess-Martin periodane;
In
tetrahydrofuran; methanol; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: hydrogen; palladium on activated charcoal / methanol / 15 h / 30 °C / 1034.32 Torr
2.1: water; lithium hydroxide monohydrate / methanol / 2 h / 20 °C
2.2: pH Ca.3
3.1: dimethylsulfide borane complex / tetrahydrofuran / 16 h / 0 - 30 °C
4.1: Dess-Martin periodane / dichloromethane / 2 h / 0 °C
With
lithium hydroxide monohydrate; dimethylsulfide borane complex; palladium on activated charcoal; water; hydrogen; Dess-Martin periodane;
In
tetrahydrofuran; methanol; dichloromethane;
