2-CYCLOPENTYL-2,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDINE-5-CARBOXYLIC ACID, TERT-BUTYL ESTER

Base Information

• Chemical Name: 2-CYCLOPENTYL-2,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDINE-5-CARBOXYLIC ACID, TERT-BUTYL ESTER
• CAS No.: 949922-59-2
• Molecular Formula: C₁₆H₂₅N₃O₂
• Molecular Weight: 291.393
• Mol file: 949922-59-2.mol

Synonyms:2-CYCLOPENTYL-2,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDINE-5-CARBOXYLIC ACID, TERT-BUTYL ESTER

Chemical Property of 2-CYCLOPENTYL-2,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDINE-5-CARBOXYLIC ACID, TERT-BUTYL ESTER

Chemical Property:

• Boiling Point: 431.7±45.0 °C(Predicted)
• PKA: 2.53±0.20(Predicted)
• PSA: 47.36000
• Density: 1.22±0.1 g/cm3(Predicted)
• LogP: 3.22930

Purity/Quality:

99%min ^*data from raw suppliers

2-CYCLOPENTYL-2,4,6,7-TETRAHYDRO-5H-PYRAZOLO-[4,3-C]PYRIDINE-5-CARBOXYLIC ACID TERT-BUTYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-CYCLOPENTYL-2,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDINE-5-CARBOXYLIC ACID, TERT-BUTYL ESTER

There total 1 articles about 2-CYCLOPENTYL-2,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDINE-5-CARBOXYLIC ACID, TERT-BUTYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Cyclopentyl bromide (137-43-9) + 1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine-5-carboxylic acid tert-butyl ester (230301-11-8,924869-27-2) → tert-butyl 1-cyclopentyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate + tert-butyl 2-cyclopentyl-6,7-dihydro-2H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate (949922-59-2)

Guidance literature:

1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine-5-carboxylic acid tert-butyl ester; With potassium tert-butylate; In dimethyl sulfoxide; at 25 ℃; for 0.0833333h; Inert atmosphere;

Cyclopentyl bromide; In dimethyl sulfoxide; at 120 ℃; for 1h; Inert atmosphere; Microwave irradiation;

upstream raw materials:

Cyclopentyl bromide

1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine-5-carboxylic acid tert-butyl ester

Refernces