5-Bromo-4-(4-chlorophenyl)thiazol-2-amine

Base Information

Chemical Name:5-Bromo-4-(4-chlorophenyl)thiazol-2-amine
CAS No.:343946-25-8
Molecular Formula:C₉H₆BrClN₂S
Molecular Weight:289.583
Hs Code.:2934100090
DSSTox Substance ID:DTXSID60513666
Wikidata:Q82373587
Mol file:343946-25-8.mol

Synonyms:5-Bromo-4-(4-chlorophenyl)thiazol-2-amine;343946-25-8;5-bromo-4-(4-chlorophenyl)-1,3-thiazol-2-amine;SCHEMBL12495409;DTXSID60513666;AKOS022175885

Suppliers and Price of 5-Bromo-4-(4-chlorophenyl)thiazol-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
5-bromo-4-(4-chlorophenyl)thiazol-2-amine 95%
1g
$ 720.00

Total 3 raw suppliers

Chemical Property of 5-Bromo-4-(4-chlorophenyl)thiazol-2-amine

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:420.239°C at 760 mmHg
Flash Point:207.953°C
PSA：67.88000
Density:1.725g/cm³
LogP:3.73830
XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:287.91236
Heavy Atom Count:14
Complexity:199

Purity/Quality:

≥99% ^*data from raw suppliers

5-bromo-4-(4-chlorophenyl)thiazol-2-amine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=C(SC(=N2)N)Br)Cl

Technology Process of 5-Bromo-4-(4-chlorophenyl)thiazol-2-amine

There total 1 articles about 5-Bromo-4-(4-chlorophenyl)thiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 343946-25-8
5-bromo-4-(4-chlorophenyl)thiazol-2-amine

Guidance literature:: With N-Bromosuccinimide; In N,N-dimethyl-formamide; at 0 - 30 ℃; for 12h;

Reference yield:

: 343946-25-8
5-bromo-4-(4-chlorophenyl)thiazol-2-amine

: 1-(5-bromo-4-(4-chlorophenyl)thiazol-2-yl)pyrrolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / chloroform / 48 h / 20 °C

2: piperidine / toluene / 24 h / Reflux

With piperidine; potassium carbonate; In chloroform; toluene;
DOI:10.1007/s00044-015-1371-3

Reference yield:

: 343946-25-8
5-bromo-4-(4-chlorophenyl)thiazol-2-amine

: 108-95-2,27073-41-2
phenol

: 1391979-53-5
N-[4-(4-chlorophenyl)-5-(phenyloxy)-1,3-thiazol-2-yl]-2-[4-(ethylsulfonyl)phenyl]acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: caesium carbonate / acetone / 7 h / 55 °C

2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 72 h / 20 °C

With benzotriazol-1-ol; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; acetone;
DOI:10.1016/j.bmc.2015.07.068