Tetranor-PGDM

Base Information

Chemical Name:Tetranor-PGDM
CAS No.:70803-91-7
Molecular Formula:C₁₆H₂₄O₇
Molecular Weight:328.362
Hs Code.:
Mol file:70803-91-7.mol

Synonyms:tetranor-prostaglandin D metabolite;tetranor-prostaglandin A metabolite;

Suppliers and Price of Tetranor-PGDM

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Tetranor-PGDM
1mg
$ 1100.00

Medical Isotopes, Inc.
Tetranor-PGDM
10 mg
$ 9000.00

Cayman Chemical
tetranor-PGDM ≥90%
100μg
$ 475.00

Cayman Chemical
tetranor-PGDM ≥90%
50μg
$ 251.00

Cayman Chemical
tetranor-PGDM ≥90%
25μg
$ 132.00

Total 2 raw suppliers

Chemical Property of Tetranor-PGDM

Chemical Property:

PSA：128.97000
LogP:1.41160

Purity/Quality:

99% ^*data from raw suppliers

Tetranor-PGDM ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Tetranor-PGDM is an abundant urinary metabolite of prostaglandin D2, a cyclooxygenase (COX) product of arachidonic acid that activates D prostanoid receptors to modulate vascular, platelet, and leuko cyte function. Tetranor-PGDM is an abundant urinary metabolite of prostaglandin D2, a cyclooxygenase (COX) product of arachidonic acid that activates D prostanoid receptors to modulate vascular, platelet, and leukocyte function.

Technology Process of Tetranor-PGDM

There total 13 articles about Tetranor-PGDM which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 1352751-82-6
C₂₁H₃₂O₈

: 70803-91-7
tetranorprostaglandin D metabolite

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃;

Reference yield:

: 5299-60-5
6-hydroxy-hexanoic acid ethyl ester

: 70803-91-7
tetranorprostaglandin D metabolite

Guidance literature:: Multi-step reaction with 13 steps

1.1: 1H-imidazole / N,N-dimethyl-formamide / Cooling with ice

2.1: n-butyllithium / tetrahydrofuran; hexanes / -75 °C / Inert atmosphere

2.2: 1 h / -75 °C

3.1: lithium chloride / tetrahydrofuran / 20 °C

3.2: 1 h / -10 °C / Inert atmosphere

4.1: hydrogen / Lindlar's catalyst / ethyl acetate

5.1: sodium tetrahydroborate; methanol / 0.5 h / -7 °C

6.1: 1H-imidazole / N,N-dimethyl-formamide / Cooling with ice

7.1: diisobutylaluminium hydride / toluene / 1 h / -70 °C / Inert atmosphere

8.1: n-butyllithium / tetrahydrofuran / Inert atmosphere; Cooling with ice

9.1: pyridinium p-toluenesulfonate / dichloromethane / 20 °C

10.1: 9-bora-bicyclo[3.3.1]nonane; dihydrogen peroxide / tetrahydrofuran / 3 h / Inert atmosphere; Cooling with ice

11.1: tetrabutyl ammonium fluoride / tetrahydrofuran

12.1: Jones reagent / water; acetone / 1 h / 0 °C

13.1: trifluoroacetic acid / dichloromethane / 20 °C

With 1H-imidazole; methanol; sodium tetrahydroborate; Jones reagent; n-butyllithium; tetrabutyl ammonium fluoride; hydrogen; dihydrogen peroxide; pyridinium p-toluenesulfonate; diisobutylaluminium hydride; 9-bora-bicyclo[3.3.1]nonane; trifluoroacetic acid; lithium chloride; Lindlar's catalyst; In tetrahydrofuran; hexanes; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; acetone; toluene;

Reference yield:

: C₂₇H₅₀O₅Si₂

: 70803-91-7
tetranorprostaglandin D metabolite

Guidance literature:: Multi-step reaction with 10 steps

1: hydrogen / Lindlar's catalyst / ethyl acetate

2: sodium tetrahydroborate; methanol / 0.5 h / -7 °C

3: 1H-imidazole / N,N-dimethyl-formamide / Cooling with ice

4: diisobutylaluminium hydride / toluene / 1 h / -70 °C / Inert atmosphere

5: n-butyllithium / tetrahydrofuran / Inert atmosphere; Cooling with ice

6: pyridinium p-toluenesulfonate / dichloromethane / 20 °C

7: 9-bora-bicyclo[3.3.1]nonane; dihydrogen peroxide / tetrahydrofuran / 3 h / Inert atmosphere; Cooling with ice

8: tetrabutyl ammonium fluoride / tetrahydrofuran

9: Jones reagent / water; acetone / 1 h / 0 °C

10: trifluoroacetic acid / dichloromethane / 20 °C

With 1H-imidazole; methanol; sodium tetrahydroborate; Jones reagent; n-butyllithium; tetrabutyl ammonium fluoride; hydrogen; dihydrogen peroxide; pyridinium p-toluenesulfonate; diisobutylaluminium hydride; 9-bora-bicyclo[3.3.1]nonane; trifluoroacetic acid; Lindlar's catalyst; In tetrahydrofuran; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; acetone; toluene;