4-Bromo-3-ethyl-1H-pyrazole

Base Information

• Chemical Name: 4-Bromo-3-ethyl-1H-pyrazole
• CAS No.: 15802-79-6
• Molecular Formula: C5H7BrN2
• Molecular Weight: 175.02648
• Hs Code.: 2933199090
• European Community (EC) Number: 801-032-5
• DSSTox Substance ID: DTXSID50502741
• Wikidata: Q82356020
• Mol file: 15802-79-6.mol

Synonyms:4-Bromo-3-ethyl-1H-pyrazole;15802-79-6;4-BROMO-5-ETHYL-1H-PYRAZOLE;1H-pyrazole, 4-bromo-3-ethyl-;4-Bromo-3-ethylpyrazole;SCHEMBL256092;DTXSID50502741;QJIWUPJCGOTRMI-UHFFFAOYSA-N;MFCD16620172;AKOS015959728;AB65712;FS-6452;CS-0315135;EN300-746381;A883458

Chemical Property of 4-Bromo-3-ethyl-1H-pyrazole

Chemical Property:

• PSA: 28.68000
• LogP: 1.73460
• Storage Temp.: 2-8°C
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 173.97926
• Heavy Atom Count: 8
• Complexity: 76.8

Purity/Quality:

97% ^*data from raw suppliers

4-bromo-3-ethyl-1H-Pyrazole 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCC1=C(C=NN1)Br

Technology Process of 4-Bromo-3-ethyl-1H-pyrazole

There total 1 articles about 4-Bromo-3-ethyl-1H-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-ethyl-1H-pyrazole (13808-71-4) → 4-bromo-3-ethyl-1H-pyrazole (15802-79-6)

Guidance literature:

Reference yield: 81.0%

4-bromo-3-ethyl-1H-pyrazole (15802-79-6) + p-toluenesulfonyl chloride (98-59-9) → 4-bromo-3-ethyl-1-tosyl-1H-pyrazole

Guidance literature:

With sodium hydroxide; In dichloromethane; water; at 38 ℃; for 16h;

DOI:10.1021/acs.jmedchem.8b00782

Reference yield:

4-bromo-3-ethyl-1H-pyrazole (15802-79-6) → N-(5-(3-ethyl-1-(thiazol-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-2,6-difluorobenzamide

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 20 °C

1.2: 20 - 90 °C

2.1: potassium phosphate; bis(di-tert-?butyl(4-?dimethylaminophenyl)?phosphine)?dichloropalladium(II) / 1,4-dioxane; acetonitrile; water / 3 h / 90 °C

3.1: dmap; N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 20 °C

4.1: sodium hydroxide / water; tetrahydrofuran; methanol

With dmap; potassium phosphate; bis(di-tert-?butyl(4-?dimethylaminophenyl)?phosphine)?dichloropalladium(II); sodium hydride; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;

upstream raw materials:

3-ethyl-1H-pyrazole

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 15802-79-6 4-Bromo-3-ethyl-1H-pyrazole

Send

Send

Metric Ton KG G Pound L ML

Send

Send