(1-ISOPROPYLPYRROLIDIN-3-YL)METHYLAMINE

Base Information

• Chemical Name: (1-ISOPROPYLPYRROLIDIN-3-YL)METHYLAMINE
• CAS No.: 90203-08-0
• Molecular Formula: C8H18N2
• Molecular Weight: 142.244
• Hs Code.: 2933990090
• Mol file: 90203-08-0.mol

Synonyms:(1-ISOPROPYLPYRROLIDIN-3-YL)METHYLAMINE;(1-ISOPROPYL-3-PYRROLIDINYL)METHANAMINE;1-(1-ISOPROPYLPYRROLIDIN-3-YL)METHANAMINE;1-(1-METHYLETHYL)-3-PYRROLIDINEMETHANAMINE;ALINDA 14421;C-(1-ISOPROPYL-PYRROLIDIN-3-YL)-METHYLAMINE;OTAVA-BB 1084324;UKRORGSYN-BB BBV-075247

Chemical Property of (1-ISOPROPYLPYRROLIDIN-3-YL)METHYLAMINE

Chemical Property:

• Vapor Pressure: 1.279mmHg at 25°C
• Boiling Point: 173.241°C at 760 mmHg
• Flash Point: 58.96°C
• PSA: 29.26000
• Density: 0.908g/cm³
• LogP: 1.31360

Purity/Quality:

97% ^*data from raw suppliers

1-(1-isopropylpyrrolidin-3-yl)methanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (1-ISOPROPYLPYRROLIDIN-3-YL)METHYLAMINE

There total 1 articles about (1-ISOPROPYLPYRROLIDIN-3-YL)METHYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (1-isopropylpyrrolidin-3-yl)methylamine (90203-08-0)

Guidance literature:

1-Isopropyl-5-oxo-3-pyrrolidincarboxamid, LiAlH4 in THF;

Reference yield: 38.0%

2-(2-fluoro-4-methoxyphenyl)-5,7-dimethoxy-quinazolin-4(3H)-one + (1-isopropylpyrrolidin-3-yl)methylamine (90203-08-0) → 2-(2-(((1-isopropylpyrrolidin-3-yl)methyl)amino)-4-methoxyphenyl)-5,7-dimethoxyquinazolin-4(3H)-one

Guidance literature:

With lithium hexamethyldisilazane; In tetrahydrofuran; for 19h; Reflux;

Reference yield: 5.0%

lithium 1-benzyl-2-(1,5-dimethyl-6-oxo-1,6-dihydropyridin-3-yl)-1H-imidazole-4-carboxylate + (1-isopropylpyrrolidin-3-yl)methylamine (90203-08-0) → rac-1-benzyl-2-(1,5-dimethyl-6-oxo-1,6-dihydropyridin-3-yl)-N-((1-isopropylpyrrolidin-3-yl)methyl)-1H-imidazole-4-carboxamide

Guidance literature:

lithium 1-benzyl-2-(1,5-dimethyl-6-oxo-1,6-dihydropyridin-3-yl)-1H-imidazole-4-carboxylate; (1-isopropylpyrrolidin-3-yl)methylamine; With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃; for 2h; Sealed tube;

With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine; In ethyl acetate; N,N-dimethyl-formamide; at 20 ℃; for 1h; Sealed tube;

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