5-Amino-2-(3-methyl-1-piperidinyl)benzoic acid

Base Information

Chemical Name:5-Amino-2-(3-methyl-1-piperidinyl)benzoic acid
CAS No.:78243-67-1
Molecular Formula:C13H18N2O2
Molecular Weight:234.298
Hs Code.:
DSSTox Substance ID:DTXSID80443779

Synonyms:78243-67-1;5-AMINO-2-(3-METHYL-1-PIPERIDINYL)BENZOIC ACID;5-Amino-2-(3-methylpiperidin-1-yl)benzoic acid;CHEMBRDG-BB 7651776;SCHEMBL9223541;DTXSID80443779;MFCD08691778;AKOS005795696;BS-36226;CS-0455785;5-Amino-2-(3-methylpiperidin-1-yl)benzoicacid

Suppliers and Price of 5-Amino-2-(3-methyl-1-piperidinyl)benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 5-Amino-2-(3-methyl-1-piperidinyl)benzoic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:451.159°C at 760 mmHg
Flash Point:226.653°C
Density:1.192g/cm³
XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:234.136827821
Heavy Atom Count:17
Complexity:283

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCCN(C1)C2=C(C=C(C=C2)N)C(=O)O

Technology Process of 5-Amino-2-(3-methyl-1-piperidinyl)benzoic acid

There total 3 articles about 5-Amino-2-(3-methyl-1-piperidinyl)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 78243-26-2
2-(3-methyl-piperidin-1-yl)-5-nitro-benzoic acid

: 78243-67-1
5-amino-2-(3-methyl-piperidin-1-yl)-benzoic acid

Guidance literature:: With hydrogen; palladium on activated charcoal; In N,N-dimethyl-formamide; at 20 ℃; for 1h; under 750.06 Torr;
DOI:10.1021/jm9810349

Reference yield:

: 2516-96-3
2-chloro-5-nitrobenzoic acid

: 78243-67-1
5-amino-2-(3-methyl-piperidin-1-yl)-benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 7 h / Heating

2: H₂ / 10 percent Pd/C / dimethylformamide / 1 h / 20 °C / 750.06 Torr

With hydrogen; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm9810349

Reference yield:

: 626-56-2,53152-98-0
3-Methylpiperidine

: 78243-67-1
5-amino-2-(3-methyl-piperidin-1-yl)-benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 7 h / Heating

2: H₂ / 10 percent Pd/C / dimethylformamide / 1 h / 20 °C / 750.06 Torr

With hydrogen; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm9810349