Methyl 2-(acetylamino)-2-deoxy-α-D-altropyranoside 6-(p-methylbenzenesulfonate)

Base Information

• Chemical Name: Methyl 2-(acetylamino)-2-deoxy-α-D-altropyranoside 6-(p-methylbenzenesulfonate)
• CAS No.: 17495-04-4
• Molecular Weight: 389.42
• Mol file: 17495-04-4.mol

Synonyms:Methyl 2-(acetylamino)-2-deoxy-α-D-altropyranoside 6-(p-methylbenzenesulfonate)

Chemical Property of Methyl 2-(acetylamino)-2-deoxy-α-D-altropyranoside 6-(p-methylbenzenesulfonate)

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methyl 2-(acetylamino)-2-deoxy-α-D-altropyranoside 6-(p-methylbenzenesulfonate)

There total 14 articles about Methyl 2-(acetylamino)-2-deoxy-α-D-altropyranoside 6-(p-methylbenzenesulfonate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

methyl N-acetyl-D-glucosamine (3055-46-7,3946-01-8,5627-24-7,6082-04-8,6082-22-0,17327-09-2,22256-76-4,32087-35-7,32087-36-8,95341-97-2,114029-61-7,114612-10-1,114612-13-4,116559-74-1) + p-toluenesulfonyl chloride (98-59-9) → ((2R,3S,4R,5R,6S)-5-acetamido-3,4-dihydroxy-6-methoxytetrahydro-2H-pyran-2-yl)methyl 4-methylbenzenesulfonate (53756-24-4,17495-04-4)

Guidance literature:

With pyridine; at 20 ℃; for 24h;

DOI:10.1021/acs.langmuir.9b02704

Reference yield: 45.0%

methyl N-acetyl-D-glucosamine (3055-46-7,3946-01-8,5627-24-7,6082-04-8,6082-22-0,17327-09-2,22256-76-4,32087-35-7,32087-36-8,95341-97-2,114029-61-7,114612-10-1,114612-13-4,116559-74-1) + p-toluenesulfonyl chloride (98-59-9) → methyl 2-acetamido-2-deoxy-6-O-p-tolylsulfonyl-β-D-glucopyranoside (375824-36-5,17495-04-4) + ((2R,3S,4R,5R,6S)-5-acetamido-3,4-dihydroxy-6-methoxytetrahydro-2H-pyran-2-yl)methyl 4-methylbenzenesulfonate (53756-24-4,17495-04-4)

Guidance literature:

With pyridine; at -10 - 20 ℃;

DOI:10.1016/j.carres.2008.02.001

Reference yield: 45.0%

methyl N-acetyl-D-glucosamine (3055-46-7,3946-01-8,5627-24-7,6082-04-8,6082-22-0,17327-09-2,22256-76-4,32087-35-7,32087-36-8,95341-97-2,114029-61-7,114612-10-1,114612-13-4,116559-74-1) + p-toluenesulfonyl chloride (98-59-9) → methyl 2-acetamido-2-deoxy-6-O-p-tolylsulfonyl-β-D-glucopyranoside (375824-36-5,17495-04-4) + ((2R,3S,4R,5R,6S)-5-acetamido-3,4-dihydroxy-6-methoxytetrahydro-2H-pyran-2-yl)methyl 4-methylbenzenesulfonate (53756-24-4,17495-04-4)

Guidance literature:

With pyridine; at -10 - 20 ℃;

DOI:10.1016/j.carres.2008.02.001

upstream raw materials:

p-toluenesulfonyl chloride

methyl N-acetyl-β-D-glucosaminide

methyl 2-acetamido-3,4,6-O-triacetyl-2-deoxy-β-D-glucopyranoside

methyl N-acetyl-D-glucosamine