3-Oxo-16β-acetoxy-14,15β-epoxy-5β-bufa-20,22-dienolide

Base Information

• Chemical Name: 3-Oxo-16β-acetoxy-14,15β-epoxy-5β-bufa-20,22-dienolide
• CAS No.: 6869-66-5
• Molecular Formula: C26H32O6
• Molecular Weight: 440.52868
• Mol file: 6869-66-5.mol

Synonyms:16β-Acetyloxy-14,15β-epoxy-3-oxo-5β-bufa-20,22-dienolide;3-Ketocinobufagin;3-Oxo-16β-acetoxy-14,15β-epoxy-5β-bufa-20,22-dienolide;3-Oxocinobufagin;Cinobufagone

Chemical Property of 3-Oxo-16β-acetoxy-14,15β-epoxy-5β-bufa-20,22-dienolide

Chemical Property:

• Melting Point: 258 - 259 °C
• PSA: 86.11000
• LogP: 4.00810

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Oxo-16β-acetoxy-14,15β-epoxy-5β-bufa-20,22-dienolide

There total 4 articles about 3-Oxo-16β-acetoxy-14,15β-epoxy-5β-bufa-20,22-dienolide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-oxo-cinobufagin (6869-66-5)

Guidance literature:

With chromium(VI) oxide; acetic acid;

DOI:10.1002/hlca.19580410721

Reference yield:

→ Acetic acid (5R,10S)-10,13-dimethyl-3-oxo-17-(6-oxo-6H-pyran-3-yl)-hexadecahydro-20-oxa-cyclopropa[14,15]cyclopenta[a]phenanthren-16-yl ester (6869-66-5)

Guidance literature:

Aus Verb.5b , CrO3 / Eg.;

DOI:10.1021/jo00798a015

Reference yield:

→ Cinobufagon (6869-66-5)

Guidance literature:

aus 5b, CrO3, AcOH;

DOI:10.1021/jo00798a015

Downstream raw materials:

3α-hydroxycinobufagin