5-NITRO-2-P-TOLYL-1H-BENZOIMIDAZOLE

Base Information

• Chemical Name: 5-NITRO-2-P-TOLYL-1H-BENZOIMIDAZOLE
• CAS No.: 1571-90-0
• Molecular Formula: C14H11N3O2
• Molecular Weight: 253.26
• Hs Code.: 2933990090
• Mol file: 1571-90-0.mol

Synonyms:ZERENEX E/6023016;ASISCHEM D50990;5-NITRO-2-P-TOLYL-1H-BENZOIMIDAZOLE;AKOS BB-7921;1H-BENZIMIDAZOLE, 2-(4-METHYLPHENYL)-5-NITRO-;5-Nitro-2-(4-Methylphenyl)benziMidazole, 95%

Chemical Property of 5-NITRO-2-P-TOLYL-1H-BENZOIMIDAZOLE

Chemical Property:

• PSA: 74.50000
• LogP: 3.96970

Purity/Quality:

99% ^*data from raw suppliers

1H-BENZIMIDAZOLE, 2-(4-METHYLPHENYL)-5-NITRO- 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-NITRO-2-P-TOLYL-1H-BENZOIMIDAZOLE

There total 16 articles about 5-NITRO-2-P-TOLYL-1H-BENZOIMIDAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

4-methyl-benzoyl chloride (874-60-2) + 4-Nitrophenylene-1,2-diamine (99-56-9) → 2-(4-methylphenyl)-6-nitro-1H-benzo[d]imidazole (1571-90-0)

Guidance literature:

4-methyl-benzoyl chloride; 4-Nitrophenylene-1,2-diamine; In dichloromethane; at 0 - 20 ℃; for 0.416667h;

With MCM-41; In dichloromethane; for 2h; Reflux;

DOI:10.1002/jccs.200800166

Reference yield: 88.0%

4-methyl-benzaldehyde (104-87-0) + 4-Nitrophenylene-1,2-diamine (99-56-9) → 2-(4-methyl-phenyl)-5-nitro-1H-benzimidazole (1571-90-0)

Guidance literature:

With MCM-41-SO₃H mesoporous nanoparticles; In water; at 20 ℃; for 0.416667h; chemoselective reaction;

DOI:10.1515/hc-2011-0056

Reference yield: 85.0%

p-Toluic acid (99-94-5) + 4-Nitrophenylene-1,2-diamine (99-56-9) → 2-(4-methyl-phenyl)-5-nitro-1H-benzimidazole (1571-90-0)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; at 150 ℃;

DOI:10.1016/j.ejmech.2019.06.054

upstream raw materials:

4-methyl-benzaldehyde

4-Nitrophenylene-1,2-diamine

3-(4-methylphenyl)isoxazol-5(4H)-one

2-iodo-4-nitrophenylamine

Downstream raw materials:

1,3-dimethyl-5-nitro-2-p-tolyl-benzimidazolium; iodide

1-methyl-6-nitro-2-p-tolyl-1H-benzimidazole

N-(2-p-tolyl-1H-benzo[d]imidazol-6-yl)quinolin-4-amine

2-p-tolyl-1H-benzo[d]imidazole-5-amine