7-Hydroxy AMinopterin

Base Information

• Chemical Name: 7-Hydroxy AMinopterin
• CAS No.: 97772-99-1
• Molecular Formula: C₁₉H₂₀N₈O₆
• Molecular Weight: 456.418
• Mol file: 97772-99-1.mol

Synonyms:7-Hydroxy AMinopterin;N-[4-[[(2,4-DiaMino-1,7-dihydro-7-oxo-6-pteridinyl)Methyl]aMino]benzoyl]- L-GlutaMic Acid;N-[4-[[(2,4-DiaMino-7,8-dihydro-7-oxo-6-pteridinyl)Methyl]aMino]benzoyl]-L-glutaMic Acid;N-[p-[[(2,4-DiaMino-7-hydroxy-6-pteridinyl)Methyl]aMino]benzoyl]-L-glutaMic Acid

Chemical Property of 7-Hydroxy AMinopterin

Chemical Property:

• PSA: 240.03000
• LogP: 0.51260

Purity/Quality:

95% ^*data from raw suppliers

7-Hydroxy Aminopterin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: The 7-hydroxy metabolite of Aminopterin (A628850) as substrate for folylpolyglutamate synthetase (FPGS).

Technology Process of 7-Hydroxy AMinopterin

There total 1 articles about 7-Hydroxy AMinopterin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ N-{4-[(2,4-diamino-7-oxo-7,8-dihydro-pteridin-6-ylmethyl)-amino]-benzoyl}-L-glutamic acid (97772-99-1)

Guidance literature:

With bromine; und anschliessenden Umsetzung mit N-<4-Amino-benzoyl>-L-glutaminsaeure und Erhitzen mit H2O;