N-L-Alanyl-L-glutamic Acid Bis(tert-butyl) Ester

Base Information

Chemical Name:N-L-Alanyl-L-glutamic Acid Bis(tert-butyl) Ester
CAS No.:45272-19-3
Molecular Formula:C16H30N2O5
Molecular Weight:330.4198
Hs Code.:
DSSTox Substance ID:DTXSID20705747
Mol file:45272-19-3.mol

Synonyms:45272-19-3;N-L-Alanyl-L-glutamic Acid Bis(tert-butyl) Ester;Di-tert-butyl L-alanyl-L-glutamate;ditert-butyl (2S)-2-[[(2S)-2-aminopropanoyl]amino]pentanedioate;SCHEMBL8722976;DTXSID20705747;A846304;(S)-Di-tert-butyl 2-((S)-2-aminopropanamido)pentanedioate;L-Glutamic acid, L-alanyl-, bis(1,1-dimethylethyl) ester

Suppliers and Price of N-L-Alanyl-L-glutamic Acid Bis(tert-butyl) Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-L-Alanyl-L-glutamicAcidBis(tert-butyl)Ester
1g
$ 1540.00

Total 3 raw suppliers

Chemical Property of N-L-Alanyl-L-glutamic Acid Bis(tert-butyl) Ester

Chemical Property:

PSA：111.21000
LogP:2.82260
XLogP3:1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:10
Exact Mass:330.21547206
Heavy Atom Count:23
Complexity:435

Purity/Quality:

97% ^*data from raw suppliers

N-L-Alanyl-L-glutamicAcidBis(tert-butyl)Ester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)NC(CCC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)N
Isomeric SMILES:C[C@@H](C(=O)N[C@@H](CCC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)N
Uses N-L-Alanyl-L-glutaMic Acid Bis(1,1-diMethylethyl) Ester is a protected amino acid pair used in polypeptide synthesis.

Technology Process of N-L-Alanyl-L-glutamic Acid Bis(tert-butyl) Ester

There total 5 articles about N-L-Alanyl-L-glutamic Acid Bis(tert-butyl) Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: C₂₄H₃₆N₂O₇

: 45272-19-3
(S)-di-tert-butyl 2-((S)-2-aminopropanamido)pentanedioate

Guidance literature:: With methanol; palladium on activated charcoal;

Reference yield:

: C₃₁H₄₀N₂O₇

: 45272-19-3
(S)-di-tert-butyl 2-((S)-2-aminopropanamido)pentanedioate

Guidance literature:: With piperidine; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

Reference yield:

: 32677-01-3
L-glutamic acid di-tert-butyl ester hydrochloride

: 45272-19-3
(S)-di-tert-butyl 2-((S)-2-aminopropanamido)pentanedioate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate / dichloromethane / 0 - 20 °C

2: piperidine / N,N-dimethyl-formamide / 1 h / 20 °C

With piperidine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; In dichloromethane; N,N-dimethyl-formamide;