4-(4-methylpiperazin-1-yl)-2-(2,2,2-trifluoro-N-(tetrahydro-2H-pyran-4-yl)acetamido)benzoic acid

Base Information

Chemical Name:4-(4-methylpiperazin-1-yl)-2-(2,2,2-trifluoro-N-(tetrahydro-2H-pyran-4-yl)acetamido)benzoic acid
CAS No.:1034975-61-5
Molecular Formula:C₁₉H₂₄F₃N₃O₄
Molecular Weight:415.412
Hs Code.:
Mol file:1034975-61-5.mol

Synonyms:4-(4-methylpiperazin-1-yl)-2-(2,2,2-trifluoro-N-(tetrahydro-2H-pyran-4-yl)acetamido)benzoic acid

Suppliers and Price of 4-(4-methylpiperazin-1-yl)-2-(2,2,2-trifluoro-N-(tetrahydro-2H-pyran-4-yl)acetamido)benzoic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 9 raw suppliers

Chemical Property of 4-(4-methylpiperazin-1-yl)-2-(2,2,2-trifluoro-N-(tetrahydro-2H-pyran-4-yl)acetamido)benzoic acid

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-(4-methylpiperazin-1-yl)-2-(2,2,2-trifluoro-N-(tetrahydro-2H-pyran-4-yl)acetamido)benzoic acid

There total 1 articles about 4-(4-methylpiperazin-1-yl)-2-(2,2,2-trifluoro-N-(tetrahydro-2H-pyran-4-yl)acetamido)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1034975-61-5
4-(4-methylpiperazin-1-yl)-2-(2,2,2-trifluoro-N-(tetrahydro-2H-pyran-4-yl)acetamido)benzoic acid

Guidance literature:: In dichloromethane; at 20 ℃;

Reference yield: 77.0%

: 1034975-61-5
4-(4-methylpiperazin-1-yl)-2-(2,2,2-trifluoro-N-(tetrahydro-2H-pyran-4-yl)acetamido)benzoic acid

: 1392150-90-1
(4-(4-methylpiperazin-1-yl)-2-((tetrahydro-2H-pyran-4-yl)amino)phenyl)methanol

Guidance literature:: 4-(4-methylpiperazin-1-yl)-2-(2,2,2-trifluoro-N-(tetrahydro-2H-pyran-4-yl)acetamido)benzoic acid; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 4h;

With water; sodium hydrogencarbonate; at 0 - 20 ℃;

Reference yield: 53.0%

: 1034975-61-5
4-(4-methylpiperazin-1-yl)-2-(2,2,2-trifluoro-N-(tetrahydro-2H-pyran-4-yl)acetamido)benzoic acid

: 1392150-51-4
5-[(3,5-difluorophenyl)thio]-1H-pyrazolo[3,4-b]pyridin-3-amine

: 1392150-95-6
N-(5-((3,5-difluorophenyl)thio)-1H-pyrazolo[3,4-b]pyridin-3-yl)-4-(4-methylpiperazin-1-yl)-2-(2,2,2-trifluoro-N-(tetrahydro-2H-pyran-4-yl)acetamido)benzamide

Guidance literature:: 4-(4-methylpiperazin-1-yl)-2-(2,2,2-trifluoro-N-(tetrahydro-2H-pyran-4-yl)acetamido)benzoic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 2h;

5-[(3,5-difluorophenyl)thio]-1H-pyrazolo[3,4-b]pyridin-3-amine; With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at -20 - 20 ℃;