2-methyl-1-(2-methyl-5-nitrophenylsulfonyl)-1H-benzo[d]imidazole

Base Information

Chemical Name:2-methyl-1-(2-methyl-5-nitrophenylsulfonyl)-1H-benzo[d]imidazole
CAS No.:93987-29-2
Molecular Formula:C₁₅H₁₃N₃O₄S
Molecular Weight:331.352
Hs Code.:
DSSTox Substance ID:DTXSID001010191
Wikidata:Q27075218
ChEMBL ID:CHEMBL5199342
Mol file:93987-29-2.mol

Synonyms:2-methyl-1-(2-methyl-5-nitrophenylsulfonyl)-1H-benzo(d)imidazole;BI6015

Suppliers and Price of 2-methyl-1-(2-methyl-5-nitrophenylsulfonyl)-1H-benzo[d]imidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
BI 6015
10mg
$ 452.00

TRC
BI6015
5mg
$ 45.00

Tocris
BI6015 ≥98%(HPLC)
50
$ 828.00

Tocris
BI6015 ≥98%(HPLC)
10
$ 201.00

Sigma-Aldrich
HNF4 Antagonist, BI6015 - CAS 93987-29-2 - CalbiochemThe HNF4 Antagonist, BI6, also referenced under CAS 93987-29-2, controls the biological activity of HNF4.
25mg
$ 203.00

Matrix Scientific
2-Methyl-1-(2-methyl-5-nitrophenylsulfonyl)-1H-benzo[d]imidazole 95%
250mg
$ 2406.00

Matrix Scientific
2-Methyl-1-(2-methyl-5-nitrophenylsulfonyl)-1H-benzo[d]imidazole 95%
100mg
$ 1194.00

Cayman Chemical
BI6015 ≥95%
50mg
$ 392.00

Cayman Chemical
BI6015 ≥95%
5mg
$ 49.00

Cayman Chemical
BI6015 ≥95%
10mg
$ 93.00

Total 12 raw suppliers

Chemical Property of 2-methyl-1-(2-methyl-5-nitrophenylsulfonyl)-1H-benzo[d]imidazole

Chemical Property:

PSA：106.16000
LogP:4.40230
Storage Temp.:+2C to +8C
Solubility.:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml).
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:331.06267708
Heavy Atom Count:23
Complexity:556

Purity/Quality:

99%, ^*data from raw suppliers

BI 6015 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C=C(C=C1)[N+](=O)[O-])S(=O)(=O)N2C(=NC3=CC=CC=C32)C
Description BI-6015 (93987-29-2) is a hepatocyte nuclear factor 4α (HNF4α) antagonist. HNF4α is a central regulator of gene expression in cell types that play a central role in metabolic homeostasis.1 BI-6015 binds to HNF4α with high affinity and modulates the expression of known target genes. It was shown to be selectively cytotoxic to cancer cell lines in vitro and in vivo however in vivo potency was limited by suboptimal pharmacokinetics.2 BI-6015 represents the first small molecule tool for pharmacologic modulation of HNF4α activity.2 Cell permeable.
Uses BI 6015 is a known HNF4α antagonist that represses the expression of known HNF4α target genes. Studies have shown that BI6015 are also capable of exhibiting selective cytotoxic activities against numerous tumor cell lines.

Technology Process of 2-methyl-1-(2-methyl-5-nitrophenylsulfonyl)-1H-benzo[d]imidazole

There total 1 articles about 2-methyl-1-(2-methyl-5-nitrophenylsulfonyl)-1H-benzo[d]imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: