Ethanamine, 2,2'-dithiobis[N,N-dimethyl-, hydrochloride (1:2)

Base Information

• Chemical Name: Ethanamine, 2,2'-dithiobis[N,N-dimethyl-, hydrochloride (1:2)
• CAS No.: 17339-60-5
• Molecular Formula: C₈H₂₀N₂S₂*2ClH
• Molecular Weight: 281.314
• Hs Code.: 2930909090
• Mol file: 17339-60-5.mol

Synonyms:Ethanamine, 2,2'-dithiobis[N,N-dimethyl-, hydrochloride (1:2);2,2-Dithio bis(N,N-dimethyl)ethaneamine hcl

Chemical Property of Ethanamine, 2,2'-dithiobis[N,N-dimethyl-, hydrochloride (1:2)

Chemical Property:

• Vapor Pressure: 3.94E-12mmHg at 25°C
• Boiling Point: 256.1 ºCat 760 mmHg
• Flash Point: 108.7 ºC
• PSA: 57.08000
• Density: 1.026 g/cm³
• LogP: 3.09500
• Water Solubility.: almost transparency
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 244.0834687
• Heavy Atom Count: 13
• Complexity: 85.1

Purity/Quality:

99.9% ^*data from raw suppliers

Bis(2-dimethylaminoethyl) Disulfide Dihydrochloride >98.0%(HPLC)(T) ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn,N
• Statements: 22-36-43-51/53-50/53
• Safety Statements: 22-26-36/37-61-60

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CCSSCCN(C)C.Cl

Technology Process of Ethanamine, 2,2'-dithiobis[N,N-dimethyl-, hydrochloride (1:2)

There total 2 articles about Ethanamine, 2,2'-dithiobis[N,N-dimethyl-, hydrochloride (1:2) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

captamine (108-02-1) → bis[2-(N,N-dimethylamino)ethyl]disulfide dihydrochloride (17339-60-5,114328-85-7) + 3-(2-dimethylaminoethylthio)-11-phenyl-6,11-dihydrodibenzothiepin (96122-45-1) + 11-(2-dimethylaminoethylthio)-11-phenyl-6,11-dihydrodibenzothiepin (96122-44-0)

Guidance literature:

With 11-chloro-11-phenyl-6,11-dihydro-dibenzo[b,e]thiepine; In N,N-dimethyl-formamide; at 90 ℃; for 6.5h;

DOI:10.1135/cccc19842520

Reference yield:

captamine (108-02-1) + 11-chloro-11-phenyl-6,11-dihydro-dibenzo[b,e]thiepine (68276-24-4) → bis[2-(N,N-dimethylamino)ethyl]disulfide dihydrochloride (17339-60-5,114328-85-7) + 3-(2-dimethylaminoethylthio)-11-phenyl-6,11-dihydrodibenzothiepin (96122-45-1) + 11-(2-dimethylaminoethylthio)-11-phenyl-6,11-dihydrodibenzothiepin (96122-44-0)

Guidance literature:

In N,N-dimethyl-formamide; at 90 ℃; for 6.5h; Yield given;

DOI:10.1135/cccc19842520

Reference yield:

bis[2-(N,N-dimethylamino)ethyl]disulfide dihydrochloride (17339-60-5,114328-85-7) + C24H26F6N2O4S2 + trifluoroacetic acid (76-05-1) → 4‐{[2‐(dimethylamino)ethyl]disulfanyl}‐N‐{[4-(trifluoromethoxy)phenyl]methyl}butanamide trifluoroacetic acid salt

Guidance literature:

bis[2-(N,N-dimethylamino)ethyl]disulfide dihydrochloride; With tris-(2-carboxyethyl)-phosphine hydrochloride; In dimethyl sulfoxide; at 20 ℃; for 0.166667h;

C₂₄H₂₆F₆N₂O₄S₂; With N-ethyl-N,N-diisopropylamine; In dimethyl sulfoxide;

trifluoroacetic acid; In dimethyl sulfoxide;

upstream raw materials:

captamine

11-chloro-11-phenyl-6,11-dihydro-dibenzo[b,e]thiepine

Downstream raw materials:

C₂HF₃O₂*C₁₄H₂₃N₃O₄S₃

C₂HF₃O₂*C₁₉H₂₄ClN₃O₂S₂

C₂HF₃O₂*C₂₂H₂₅N₃O₂S₂

C₂HF₃O₂*C₁₉H₂₂N₂O₂S₂

Refernces