3-(3-HYDROXY-PHENYL)-PROPIONALDEHYDE

Base Information

• Chemical Name: 3-(3-HYDROXY-PHENYL)-PROPIONALDEHYDE
• CAS No.: 26172-10-1
• Molecular Formula: C9H10O2
• Molecular Weight: 150.177
• Hs Code.: 2912499000
• Mol file: 26172-10-1.mol

Synonyms:3-(3-HYDROXY-PHENYL)-PROPIONALDEHYDE;Benzenepropanal, 3-hydroxy-;3-(3-Hydroxyphenyl)propanal

Chemical Property of 3-(3-HYDROXY-PHENYL)-PROPIONALDEHYDE

Chemical Property:

• Vapor Pressure: 0.00252mmHg at 25°C
• Boiling Point: 278.5°C at 760 mmHg
• PKA: 9.94±0.10(Predicted)
• Flash Point: 116.5°C
• PSA: 37.30000
• Density: 1.116g/cm³
• LogP: 1.52370
• Storage Temp.: 2-8°C

Purity/Quality:

96% ^*data from raw suppliers

3-(3-Hydroxy-phenyl)-propionaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(3-HYDROXY-PHENYL)-PROPIONALDEHYDE

There total 2 articles about 3-(3-HYDROXY-PHENYL)-PROPIONALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

meta-hydroxybenzaldehyde (100-83-4) → 3-(3-hydroxyphenyl)propanal (26172-10-1)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. NaOH

2: H₂ / Rh(PPh₃)3Cl

With sodium hydroxide; hydrogen; Wilkinson's catalyst;

DOI:10.1039/j39700000649

Reference yield:

→ 3-(3-hydroxyphenyl)propanal (26172-10-1)

Guidance literature:

Reference yield: 50.0%

3-(3-hydroxyphenyl)propanal (26172-10-1) + 3,5-di-tert-butylbenzoic acid (16225-26-6) → C24H30O3 (1399732-73-0)

Guidance literature:

3,5-di-tert-butylbenzoic acid; With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 0 ℃; for 1h;

3-(3-hydroxyphenyl)propanal; In dichloromethane; at 20 ℃; for 12h;

DOI:10.1021/ja305367j

upstream raw materials:

meta-hydroxybenzaldehyde

Downstream raw materials:

C₂₄H₃₀O₃

Refernces