6-methoxy-7-methyl-3,4-dihydronaphthalen-1(2H)-one

Base Information

Chemical Name:6-methoxy-7-methyl-3,4-dihydronaphthalen-1(2H)-one
CAS No.:61495-10-1
Molecular Formula:C12H14O2
Molecular Weight:190.242
Hs Code.:2914509090
DSSTox Substance ID:DTXSID90463322
Wikidata:Q82288179
Mol file:61495-10-1.mol

Synonyms:61495-10-1;6-methoxy-7-methyl-3,4-dihydronaphthalen-1(2H)-one;6-methoxy-7-methyl-3,4-dihydro-2H-naphthalen-1-one;6-METHOXY-7-METHYL-3,4-DIHYDRO-1(2H)-NAPHTHALENONE;7-methyl-6-methoxy-1-tetralone;CHEMBRDG-BB 6368122;SCHEMBL1807630;6-methoxy-7-methyl-1,2,3,4-tetrahydronaphthalen-1-one;6-Methoxy-7-methyl-1-tetralone;DTXSID90463322;XVCLHUXQMUORDD-UHFFFAOYSA-N;AM9390;MFCD00511240;AKOS005738324;SB37942;AS-68347;CS-0061348;F12698;6-methoxy-7-methyl-1,2,3,4-tetrahydro-1-naphthalenone

Suppliers and Price of 6-methoxy-7-methyl-3,4-dihydronaphthalen-1(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Methoxy-7-methyl-3,4-dihydro-2H-naphthalen-1-one
500mg
$ 310.00

J&W Pharmlab
6-Methoxy-7-methyl-3,4-dihydro-2H-naphthalen-1-one 97%
100mg
$ 137.00

J&W Pharmlab
6-Methoxy-7-methyl-3,4-dihydro-2H-naphthalen-1-one 97%
250mg
$ 175.00

Crysdot
6-Methoxy-7-methyl-3,4-dihydronaphthalen-1(2H)-one 95+%
250mg
$ 180.00

Crysdot
6-Methoxy-7-methyl-3,4-dihydronaphthalen-1(2H)-one 95+%
1g
$ 457.00

Chemenu
6-methoxy-7-methyl-3,4-dihydronaphthalen-1(2H)-one 95%
1g
$ 284.00

Chemenu
6-methoxy-7-methyl-3,4-dihydronaphthalen-1(2H)-one 95%
5g
$ 853.00

American Custom Chemicals Corporation
6-METHOXY-7-METHYL-1,2,3,4-TETRAHYDRONAPHTHALEN-1-ONE 95.00%
5MG
$ 495.15

Ambeed
6-Methoxy-7-methyl-3,4-dihydronaphthalen-1(2H)-one 95%
250mg
$ 164.00

Ambeed
6-Methoxy-7-methyl-3,4-dihydronaphthalen-1(2H)-one 95%
100mg
$ 113.00

Total 17 raw suppliers

Chemical Property of 6-methoxy-7-methyl-3,4-dihydronaphthalen-1(2H)-one

Chemical Property:

Vapor Pressure:7.01E-05mmHg at 25°C
Boiling Point:343.5°C at 760 mmHg
Flash Point:161.3°C
PSA：26.30000
Density:1.099g/cm³
LogP:2.52260
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:190.099379685
Heavy Atom Count:14
Complexity:224

Purity/Quality:

99%, ^*data from raw suppliers

6-Methoxy-7-methyl-3,4-dihydro-2H-naphthalen-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(CCCC2=O)C=C1OC

Technology Process of 6-methoxy-7-methyl-3,4-dihydronaphthalen-1(2H)-one

There total 1 articles about 6-methoxy-7-methyl-3,4-dihydronaphthalen-1(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3556-83-0
methyl 4-methyl-3-methoxybenzoate

: 61495-10-1
3,4-dihydro-6-methoxy-7-methyl-1(2H)-naphthalenone

Guidance literature:: Multi-step reaction with 5 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran / 0.17 h / 0 - 20 °C

2.1: triphenylphosphine; tetrachloromethane / 15 h / 55 - 70 °C

3.1: palladium diacetate; tributyl-amine / Microwave irradiation

3.2: 12 h / 20 °C

4.1: sodium hydroxide / tetrahydrofuran; water; ethanol / 12 h / 20 °C

5.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 0.33 h / 0 - 20 °C

5.2: 0.33 h / 0 - 20 °C

With tetrachloromethane; lithium aluminium tetrahydride; oxalyl dichloride; tributyl-amine; palladium diacetate; N,N-dimethyl-formamide; triphenylphosphine; sodium hydroxide; In tetrahydrofuran; ethanol; dichloromethane; water; 5.2: |Friedel-Crafts Acylation;
DOI:10.1021/acs.jmedchem.7b00785

Reference yield:

: 61495-10-1
3,4-dihydro-6-methoxy-7-methyl-1(2H)-naphthalenone

: 1307813-76-8
8-methyl-3-(5-phenyl-4-(trifluoromethyl)isoxazol-3-yl)-4,5-dihydronaphtho[1,2-c]isoxazole-7-carbaldehyde

Guidance literature:: Multi-step reaction with 6 steps

1.1: hydroxylamine hydrochloride; sodium acetate / methanol / 2 h / 20 - 60 °C

2.1: lithium diisopropyl amide / tetrahydrofuran / 0 °C

2.2: 0.58 h / 0 °C

3.1: boron tribromide / dichloromethane / 0 - 20 °C

4.1: pyridine / 0 - 20 °C

5.1: lithium chloride / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane / 20 - 100 °C

6.1: triethylamine; ozone; oxygen / dichloromethane / -78 - 20 °C / Inert atmosphere

With hydroxylamine hydrochloride; oxygen; sodium acetate; boron tribromide; ozone; triethylamine; lithium chloride; lithium diisopropyl amide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; 1,4-dioxane; pyridine; methanol; dichloromethane;

Reference yield:

: 61495-10-1
3,4-dihydro-6-methoxy-7-methyl-1(2H)-naphthalenone

: 1307813-77-9
8-methyl-7-(oxiran-2-yl)-3-(5-phenyl-4-(trifluoromethyl)isoxazol-3-yl)-4,5-dihydronaphtho[1,2-c]isoxazole

Guidance literature:: Multi-step reaction with 6 steps

1.1: hydroxylamine hydrochloride; sodium acetate / methanol / 2 h / 20 - 60 °C

2.1: lithium diisopropyl amide / tetrahydrofuran / 0 °C

2.2: 0.58 h / 0 °C

3.1: boron tribromide / dichloromethane / 0 - 20 °C

4.1: pyridine / 0 - 20 °C

5.1: lithium chloride / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane / 20 - 100 °C

6.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 20 °C / Inert atmosphere

With hydroxylamine hydrochloride; sodium acetate; boron tribromide; 3-chloro-benzenecarboperoxoic acid; lithium chloride; lithium diisopropyl amide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; 1,4-dioxane; pyridine; methanol; dichloromethane;