3-(4,6-DIMETHOXYPYRIMIDIN-2-YL)PROPANOIC ACID METHYL ESTER

Base Information

Chemical Name:3-(4,6-DIMETHOXYPYRIMIDIN-2-YL)PROPANOIC ACID METHYL ESTER
CAS No.:870079-64-4
Molecular Formula:C₁₀H₁₄N₂O₄
Molecular Weight:226.232
Hs Code.:2933599590
Mol file:870079-64-4.mol

Synonyms:3-(4,6-DIMETHOXYPYRIMIDIN-2-YL)PROPANOIC ACID METHYL ESTER

Suppliers and Price of 3-(4,6-DIMETHOXYPYRIMIDIN-2-YL)PROPANOIC ACID METHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
METHYL (4,6-DIMETHOXYPYRIMIDIN-2-YL)PROPANOATE 95.00%
5MG
$ 501.36

Total 2 raw suppliers

Chemical Property of 3-(4,6-DIMETHOXYPYRIMIDIN-2-YL)PROPANOIC ACID METHYL ESTER

Chemical Property:

Melting Point:119-120°C
Boiling Point:338.1±32.0 °C(Predicted)
PKA:1.50±0.30(Predicted)
PSA：70.54000
Density:1.170±0.06 g/cm3(Predicted)
LogP:0.77030

Purity/Quality:

97% ^*data from raw suppliers

METHYL (4,6-DIMETHOXYPYRIMIDIN-2-YL)PROPANOATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-(4,6-DIMETHOXYPYRIMIDIN-2-YL)PROPANOIC ACID METHYL ESTER

There total 1 articles about 3-(4,6-DIMETHOXYPYRIMIDIN-2-YL)PROPANOIC ACID METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1394162-35-6
methyl 3-(4,6-dimethoxypyrimidin-2-yl)acrylate

: 1394162-36-7
methyl 3-(4-ethoxy-6-methoxypyrimidin-2-yl)acrylate

: 870079-64-4
methyl 3-(4,6-dimethoxypyrimidin-2-yl)propanoate

: 1394162-37-8
methyl 3-(4-ethoxy-6-methoxypyrimidin-2-yl)propanoate

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 2h;

Reference yield:

: 870079-64-4
methyl 3-(4,6-dimethoxypyrimidin-2-yl)propanoate

: 1394161-07-9
5-m-tolyl-oxazole-4-carboxylic acid {1-[3-(4,6-dimethoxy-pyrimidin-2-yl)-propyl]-1H-pyrazol-4-yl}-amide

Guidance literature:: Multi-step reaction with 3 steps

1.1: diisobutylaluminium hydride / tetrahydrofuran / 0.67 h / 0 °C

1.2: 20 °C / pH 1

2.1: triethylamine / dichloromethane / 0.08 h / 20 °C

2.2: 0.5 h / 0 - 20 °C

3.1: caesium carbonate / N,N-dimethyl-formamide / 18 h / 65 °C

With diisobutylaluminium hydride; caesium carbonate; triethylamine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;