isotiod

Base Information

• Chemical Name: isotiod
• CAS No.: 57476-29-6
• Molecular Formula: C₁₈H₂₃NO₂S
• Molecular Weight: 317.452
• Mol file: 57476-29-6.mol

Synonyms:1-(p-Hydroxyphenyl)-2-(3'-phenylthiopropylamino)-1-propanol;NSC 288403

Chemical Property of isotiod

Chemical Property:

• Vapor Pressure: 1.27E-11mmHg at 25°C
• Boiling Point: 519.6°Cat760mmHg
• Flash Point: 268°C
• PSA: 77.79000
• Density: g/cm³
• LogP: 3.97700

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of isotiod

There total 2 articles about isotiod which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-phenylthiopropanol (24536-40-1) → 4-[1-Hydroxy-2-(3-phenylsulfanyl-propylamino)-propyl]-phenol (57476-29-6)

Guidance literature:

Multi-step reaction with 2 steps

1: PBr₃ / benzene / Heating

2: Et₃N / propan-2-ol / Heating

With phosphorus tribromide; triethylamine; In isopropyl alcohol; benzene;

Reference yield:

3-phenylthio-1-bromopropane (3238-98-0) + p-hydroxynorepherdine (552-85-2) → 4-[1-Hydroxy-2-(3-phenylsulfanyl-propylamino)-propyl]-phenol (57476-29-6)

Guidance literature:

With triethylamine; In isopropyl alcohol; Heating;

upstream raw materials:

3-phenylthio-1-bromopropane

p-hydroxynorepherdine

3-phenylthiopropanol