1-ETHYL-PIPERIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE

Base Information

• Chemical Name: 1-ETHYL-PIPERIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE
• CAS No.: 1185293-15-5
• Molecular Formula: C₈H₁₅NO₂*ClH
• Molecular Weight: 193.674
• Hs Code.: 2933399090
• Mol file: 1185293-15-5.mol

Synonyms:1-ETHYL-PIPERIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE;3-CARBOXY-1-ETHYL-PIPERIDINE HCL

Chemical Property of 1-ETHYL-PIPERIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE

Chemical Property:

• PSA: 40.54000
• LogP: 1.54280

Purity/Quality:

97% ^*data from raw suppliers

1-Ethyl-piperidine-3-carboxylicAcidHydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-ETHYL-PIPERIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE

There total 1 articles about 1-ETHYL-PIPERIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetaldehyde (75-07-0,9002-91-9) + (R)-nipecotic acid (498-95-3,25137-00-2,59045-82-8,60252-41-7,262853-93-0) → C8H15NO2*ClH (1185293-15-5)

Guidance literature:

acetaldehyde; (R)-nipecotic acid; With sodium cyanoborohydride; triethylamine; In methanol; dichloromethane; at 0 - 20 ℃;

With hydrogenchloride; In 1,4-dioxane;

Reference yield:

C8H15NO2*ClH (1185293-15-5) + C35H59N5O5*ClH (1141826-45-0) → C43H70N6O6 (1141824-65-8)

Guidance literature:

Multi-step reaction with 2 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0.25 h / 20 °C

2: sulfur trioxide pyridine complex; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine / dichloromethane / 0.17 h / 0 °C

With sulfur trioxide pyridine complex; benzotriazol-1-ol; dimethyl sulfoxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide;

upstream raw materials:

acetaldehyde

(R)-nipecotic acid

Downstream raw materials:

C₄₃H₇₀N₆O₆

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