4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide hydrochloride

Base Information

• Chemical Name: 4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide hydrochloride
• CAS No.: 893421-54-0
• Molecular Formula: C20H22ClN3O
• Molecular Weight: 355.867
• Mol file: 893421-54-0.mol

Synonyms:4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide hydrochloride

Chemical Property of 4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide hydrochloride

Chemical Property:

• Melting Point: 205 - 208 °C
• PSA: 60.91000
• LogP: 4.55550
• Storage Temp.: 2-8°C
• Solubility.: H2O: soluble15mg/mL, clear

Purity/Quality:

99.5% ^*data from raw suppliers

Imidafenacin hydrochloride ≥95% (HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide hydrochloride

There total 2 articles about 4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.3%

imidafenacin (170105-16-5) → 4-(2-methyl-1-imidazolyl)-2,2-diphenylbutanamide hydrochloride (893421-54-0)

Guidance literature:

With hydrogenchloride; In water; ethyl acetate; isopropyl alcohol; at 15 - 20 ℃; for 2h; Heating / reflux;

Reference yield: 79.3%

→ 4-(2-methyl-1-imidazolyl)-2,2-diphenylbutanamide hydrochloride (893421-54-0)

Guidance literature:

With hydrogenchloride; In ethyl acetate; isopropyl alcohol; at 15 - 20 ℃; for 2h; Purification / work up;

Reference yield: 92.0%

4-(2-methyl-1-imidazolyl)-2,2-diphenylbutanamide hydrochloride (893421-54-0) → imidafenacin (170105-16-5)

Guidance literature:

With sodium hydroxide; In ethanol; water; at 15 - 20 ℃; for 2h; Product distribution / selectivity; Charcoal; Cellulose powder;

upstream raw materials:

imidafenacin

Downstream raw materials:

imidafenacin

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