polyarginine

Base Information

• Chemical Name: polyarginine
• CAS No.: 25212-18-4
• Molecular Formula: C6H12N4O
• Molecular Weight: 174.20096
• Mol file: 25212-18-4.mol

Synonyms:polyarginine

Chemical Property of polyarginine

Chemical Property:

• PSA: 91.00000
• LogP: 0.32990

Purity/Quality:

98.5% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of polyarginine

There total 258 articles about polyarginine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

H-Arg-pNA (6154-84-3) → L-arginine (74-79-3,25212-18-4) + 4-nitro-aniline (100-01-6,104810-17-5)

Guidance literature:

With Tris-HCl buffer; an aminopeptidase from the seeds of Cannabis sativa; water; at 37 ℃; pH=7.5; Enzyme kinetics; Enzymatic reaction;

DOI:10.1271/bbb.64.1055

Reference yield:

L-Arg-D-Asp (275354-61-5) → (2R)-aspartic acid (1783-96-6,25608-40-6,27881-03-4,32505-46-7,52526-39-3) + L-arginine (74-79-3,25212-18-4)

Guidance literature:

With recombinant Streptomyces coelicolor Sco₃₀₅₈ dipeptidase; water; at 30 ℃; pH=8; Concentration; Kinetics; aq. buffer; Enzymatic reaction;

DOI:10.1021/bi901935y

Reference yield:

2-Benzyloxycarbonylamino-5-guanidino-pentanoic acid (1234-35-1,5619-02-3,6382-93-0) → L-arginine (74-79-3,157-06-2,7004-12-8,7200-25-1,25212-18-4) + benzyl alcohol (100-51-6,185532-71-2)

Guidance literature:

With N^α-benzyloxycarbonyl amino acid urethane hydrolase II; cobalt(II); at 33 ℃; for 0.5h; Rate constant; pH=6.5;

upstream raw materials:

L-arginine

N-α-benzoyl-DL-arginine

O-methylisourea p-toluenesulfonate

DL-ornithine hydrochloride

Downstream raw materials:

5-Guanidino-2-(2-p-tolyloxy-acetylamino)-pentanoic acid

2-[2-(4-Acetyl-phenoxy)-acetylamino]-5-guanidino-pentanoic acid

2-[2-(4-Acetylamino-phenoxy)-acetylamino]-5-guanidino-pentanoic acid

(R)-2-((S)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-5-guanidino-pentanoic acid

Refernces

• 1、 Shimada,Ishii,Nambara. "Occurrence of bufadienolides in the skin of Bufo viridis Laur.". . p. 3454 - 3457. Retrieved 1986.
• 2、 Asim, Mulazim Hussain,Gust, Ronald,Hupfauf, Andrea,Jalil, Aamir,Knabl, Ludwig,Nelles, Philipp Alexander,Shahzadi, Iram,Bernkop-Schnürch, Andreas. "Lipophilic Arginine Esters: The Gateway to Preservatives without Side Effects". . p. 3129 - 3139. Retrieved 2020.
• 3、 Fox. "". . p. 418. Retrieved 1938.
• 4、 Maehr,Blount,Pruess,Yarmchuk,Kellett. "Antimetabolites produced by microorganisms. VIII. N5 hydroxy L arginine, a new naturally occurring amino acid". . p. 284 - 288. Retrieved 1973.
• 5、 Balloo, Nandani,Fujita, Kei,Matsuda, Kenichi,Okino, Tatsufumi,Phan, Chin-Soon,Wakimoto, Toshiyuki. "Argicyclamides A-C Unveil Enzymatic Basis for Guanidine Bis-prenylation". supporting information. p. 10083 - 10087. Retrieved 2021/07/26.
• 6、 De Cesare, Silvia,McKenna, Catherine A.,Mulholland, Nicholas,Murray, Lorna,Bella, Juraj,Campopiano, Dominic J.. "Direct monitoring of biocatalytic deacetylation of amino acid substrates by1H NMR reveals fine details of substrate specificity". supporting information. p. 4904 - 4909. Retrieved 2021/06/16.