AO 128

Base Information

• Chemical Name: AO 128
• CAS No.: 112653-29-9
• Molecular Formula: C₁₀H₂₁NO₇
• Molecular Weight: 267.279
• Mol file: 112653-29-9.mol

Synonyms:2,3-Dideoxy-2-((2-hydroxy-1-(hydroxymethyl)ethyl)amino)-4-C-(hydroxymethyl)-epi-inositol; 5-(2-Hydroxy-1-(hydroxymethyl)ethyl)amino-1-C-(hydroxymethyl)-1,2,3,4-cyclohexanetetrol; BRN 5430708; CCRIS 4540; Epi-inositol, 2,3-dideoxy-2-((2-hydroxy-1-(hydroxymethyl)ethyl)amino)-4-C-(hydroxymethyl)-; 5-[(1,3-dihydroxypropan-2-yl)amino]-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol; (1S,2S,3R,4S,5S)-5-[(1,3-dihydroxypropan-2-yl)amino]-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol

Chemical Property of AO 128

Chemical Property:

• Vapor Pressure: 5.37E-17mmHg at 25°C
• Boiling Point: 601.9°C at 760 mmHg
• Flash Point: 274.1°C
• PSA: 153.64000
• Density: 1.58g/cm³
• LogP: -4.10150

Purity/Quality:

97% ^*data from raw suppliers

AO 128 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of AO 128

There total 21 articles about AO 128 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.5%

(1S)-(1(OH),2,4,5/1,3)-2,3,4-tri-O-benzyl-5-<<2-hydroxy-1-(hydroxymethyl)ethyl>amino>-1-C-<(benzyloxy)methyl>-1,2,3,4-cyclohexanetetrol (115250-39-0) → voglibose (83480-29-9,112653-29-9)

Guidance literature:

With formic acid; palladium 10% on activated carbon; hydrogen; In methanol; at 35 ℃; for 18h; Temperature; Time;

Reference yield: 85.0%

dihydroxyacetone (96-26-4,26776-70-5) + (1S,2S,3R,4S,5S)-1-amino-5-hydroxymethyl-2,3,4,5-tetrahydroxycyclohexane (83465-22-9) → voglibose (83480-29-9,112653-29-9)

Guidance literature:

With hydrogenchloride; sodium cyanoborohydride; In N,N-dimethyl-formamide; at 60 ℃; for 24h;

Reference yield: 85.0%

C42H41NO13 → voglibose (83480-29-9,112653-29-9)

Guidance literature:

In water; for 24h; Reflux;

upstream raw materials:

dihydroxyacetone

(1S,2S,3R,4S,5S)-1-amino-5-hydroxymethyl-2,3,4,5-tetrahydroxycyclohexane

(1S)-(1(OH),2,4,5/1,3)-2,3,4-tri-O-benzyl-5-<<2-hydroxy-1-(hydroxymethyl)ethyl>amino>-1-C-<(benzyloxy)methyl>-1,2,3,4-cyclohexanetetrol

(1S)-(1(OH),2,4/1,3)-2,3,4-Tri-O-benzyl-1-C-<(benzyloxy)methyl>-5-oxo-1,2,3,4-cyclohexanetetrol