6-Methoxyimidazo[2,1-b][1,3]benzothiazole-2-carboxylic acid

Base Information

Chemical Name:6-Methoxyimidazo[2,1-b][1,3]benzothiazole-2-carboxylic acid
CAS No.:113508-88-6
Molecular Formula:C11H8N2O3S
Molecular Weight:248.261
Hs Code.:
ChEMBL ID:CHEMBL267798
DSSTox Substance ID:DTXSID30555331
Wikidata:Q82436647
Mol file:113508-88-6.mol

Synonyms:113508-88-6;6-methoxyimidazo[2,1-b][1,3]benzothiazole-2-carboxylic acid;10-methoxy-7-thia-2,5-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),3,5,9,11-pentaene-4-carboxylic acid;CHEMBL267798;SCHEMBL17620857;DTXSID30555331;AKOS005893028;7-Methoxyimidazo[2,1-b][1,3]benzothiazole-2-carboxylic acid

Suppliers and Price of 6-Methoxyimidazo[2,1-b][1,3]benzothiazole-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 6-Methoxyimidazo[2,1-b][1,3]benzothiazole-2-carboxylic acid

Chemical Property:

Melting Point:270-273 °C
PKA:-4.53±0.41(Predicted)
PSA：92.07000
Density:1.60±0.1 g/cm3(Predicted)
LogP:2.25580
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:248.02556330
Heavy Atom Count:17
Complexity:328

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)N3C=C(N=C3S2)C(=O)O

Technology Process of 6-Methoxyimidazo[2,1-b][1,3]benzothiazole-2-carboxylic acid

There total 3 articles about 6-Methoxyimidazo[2,1-b][1,3]benzothiazole-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 113508-88-6
10-methoxy-7-thia-2,5-diazatricyclo[6.4.0.0²^,⁶]dodeca-1⁽⁸⁾,3,5,9,11-pentaene-4-carboxylic acid

Guidance literature:: With water; sodium hydroxide; In ethanol; at 75 ℃; for 0.75h;

Reference yield: 86.0%

: 81021-97-8
ethyl 10-methoxy-7-thia-2,5-diazatricyclo[6.4.0.0²^,⁶]dodeca-1⁽⁸⁾,3,5,9,11-pentaene-4-carboxylate

: 113508-88-6
10-methoxy-7-thia-2,5-diazatricyclo[6.4.0.0²^,⁶]dodeca-1⁽⁸⁾,3,5,9,11-pentaene-4-carboxylic acid

Guidance literature:: With sodium hydroxide; In ethanol; for 4h; Heating;
DOI:10.1021/jm00401a009

Reference yield:

: 1747-60-0
6-methoxybenzothiazol-2-ylamine

: 113508-88-6
10-methoxy-7-thia-2,5-diazatricyclo[6.4.0.0²^,⁶]dodeca-1⁽⁸⁾,3,5,9,11-pentaene-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 2.) EtOH / 1.) DME, 2.) reflux

2: 86 percent / 1N NaOH / ethanol / 4 h / Heating

With sodium hydroxide; ethanol; In ethanol;
DOI:10.1021/jm00401a009