3-(1-Piperidinylcarbonyl)phenol

Base Information

Chemical Name:3-(1-Piperidinylcarbonyl)phenol
CAS No.:15504-60-6
Molecular Formula:C12H15NO2
Molecular Weight:205.257
Hs Code.:2933399090
DSSTox Substance ID:DTXSID50429060
Wikidata:Q82241946
Mol file:15504-60-6.mol

Synonyms:15504-60-6;3-(1-PIPERIDINYLCARBONYL)PHENOL;3-[(Piperidin-1-yl)carbonyl]phenol;(3-hydroxyphenyl)(piperidin-1-yl)methanone;(3-hydroxyphenyl)-piperidin-1-ylmethanone;Oprea1_120546;1-(3-hydroxybenzoyl)piperidine;SCHEMBL4053730;DTXSID50429060;QBMGIYKRXFEBPF-UHFFFAOYSA-N;MFCD01017227;STK873628;AKOS000207504;SB43722;BS-21542;3-(1-Piperidinylcarbonyl)phenol, AldrichCPR;CS-0213492;FT-0741334

Suppliers and Price of 3-(1-Piperidinylcarbonyl)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-[(Piperidin-1-yl)carbonyl]phenol
5mg
$ 60.00

TRC
3-[(Piperidin-1-yl)carbonyl]phenol
2.5mg
$ 45.00

Crysdot
(3-Hydroxyphenyl)(piperidin-1-yl)methanone 95+%
100g
$ 790.00

Crysdot
(3-Hydroxyphenyl)(piperidin-1-yl)methanone 95+%
25g
$ 339.00

Chemenu
(3-Hydroxyphenyl)(piperidin-1-yl)methanone 95%
25g
$ 320.00

ChemBridge Corporation
3-(1-piperidinylcarbonyl)phenol 95%
250 mg
$ 31.00

American Custom Chemicals Corporation
3-(1-PIPERIDINYLCARBONYL)PHENOL 95.00%
1G
$ 685.21

American Custom Chemicals Corporation
3-(1-PIPERIDINYLCARBONYL)PHENOL 95.00%
5G
$ 1018.71

aablocks
3-[(Piperidin-1-yl)carbonyl]phenol 98%
100g
$ 934.00

aablocks
3-[(Piperidin-1-yl)carbonyl]phenol 98%
5g
$ 120.00

Total 7 raw suppliers

Chemical Property of 3-(1-Piperidinylcarbonyl)phenol

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:398.605°C at 760 mmHg
Flash Point:194.869°C
PSA：40.54000
Density:1.187g/cm³
LogP:1.95620
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:205.110278721
Heavy Atom Count:15
Complexity:224

Purity/Quality:

98% ^*data from raw suppliers

3-[(Piperidin-1-yl)carbonyl]phenol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)C(=O)C2=CC(=CC=C2)O

Technology Process of 3-(1-Piperidinylcarbonyl)phenol

There total 5 articles about 3-(1-Piperidinylcarbonyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 69001-09-8
(3-methoxyphenyl)(piperidin-1-yl)methanone

: 15504-60-6
1-(3-hydroxybenzoyl)piperidine

Guidance literature:: With boron tribromide; In dichloromethane; at -78 - 20 ℃;
DOI:10.3762/bjoc.13.151

Reference yield: 76.0%

: 110-89-4
piperidine

: 99-06-9
3-Carboxyphenol

: 15504-60-6
1-(3-hydroxybenzoyl)piperidine

Guidance literature:: With 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃; for 12h; Inert atmosphere;
DOI:10.1021/ja400082x

Reference yield:

: 586-38-9
3-Methoxybenzoic acid

: 15504-60-6
1-(3-hydroxybenzoyl)piperidine

Guidance literature:: Multi-step reaction with 2 steps

1.1: N,N-dimethyl-formamide; thionyl chloride / toluene / 0.5 h

1.2: 4 h

2.1: boron tribromide / dichloromethane / -78 - 20 °C

With thionyl chloride; boron tribromide; N,N-dimethyl-formamide; In dichloromethane; toluene;
DOI:10.3762/bjoc.13.151