4-Azido-L-homoalanine, (S)-2-Amino-4-azidobutanoic acid hydrochloride

Base Information

• Chemical Name: 4-Azido-L-homoalanine, (S)-2-Amino-4-azidobutanoic acid hydrochloride
• CAS No.: 942518-29-8
• Molecular Formula: C4H8N4O2.HCl
• Molecular Weight: 180.59286
• Hs Code.: 2929909090
• Mol file: 942518-29-8.mol

Synonyms:4-Azido-L-homoalanine, (S)-2-Amino-4-azidobutanoic acid hydrochloride;H-L-Aha-OH*HCl;(S)-2-Amino-4-azido-butanoic acid HCl;H-L-Aha-OH hydrochloride;4-Azido-L-homoalanine hydrochloride;(2S)-2-Amino-4-azidobutanoic acid hydrochloride (1:1)

Chemical Property of 4-Azido-L-homoalanine, (S)-2-Amino-4-azidobutanoic acid hydrochloride

Chemical Property:

• Melting Point: 139°C
• PSA: 113.07000
• LogP: 1.05376
• Storage Temp.: -20°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Azido-L-homoalanine hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: L-Azidohomoalanine (AHA) is an amino acid analog of methionine that contains a very small modification, specifically an azido moiety. 4-Azido-L-homoalanine, (S)-2-Amino-4-azidobutanoic acid hydrochloride can be fed to cultured cells and incorporated into proteins during active protein synthesis. Detection utilizes the chemoselective ligation or “click ” reaction between an azide and an alkyne or cyclooctyne. For example the azido-modified protein can be detected with either fluorescent alkyne or biotin alkyne. Detection sensitivity with these reagents in 1-D gels and Western blots is in the low femtomole range and compatible with downstream LC-MS/MS and MALDI-MS analysis.