Technology Process of Futoquinol
There total 6 articles about Futoquinol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 93 percent / n-BuLi / tetrahydrofuran / 1 h / -70 - -20 °C
2: 78 percent / Raney Ni / dioxane / 20 h / Heating
3: 1.) K2CO3 / 1.) acetone, reflux, 11 h, 2.) 125 grad C, 4 h
4: 51 percent / tetrahydrofuran / electrolyzis, glassy carbon anode, platinum cathode
5: 72 percent / DDQ / benzene / 24 h / Heating
With
n-butyllithium; nickel; potassium carbonate; 2,3-dicyano-5,6-dichloro-p-benzoquinone;
In
tetrahydrofuran; 1,4-dioxane; benzene;
DOI:10.1016/S0040-4039(00)94967-0
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 93 percent / n-BuLi / tetrahydrofuran / 1 h / -70 - -20 °C
2: 78 percent / Raney Ni / dioxane / 20 h / Heating
3: 1.) K2CO3 / 1.) acetone, reflux, 11 h, 2.) 125 grad C, 4 h
4: 51 percent / tetrahydrofuran / electrolyzis, glassy carbon anode, platinum cathode
5: 72 percent / DDQ / benzene / 24 h / Heating
With
n-butyllithium; nickel; potassium carbonate; 2,3-dicyano-5,6-dichloro-p-benzoquinone;
In
tetrahydrofuran; 1,4-dioxane; benzene;
DOI:10.1016/S0040-4039(00)94967-0
