Etelcalcetide

Base Information

Chemical Name:Etelcalcetide
CAS No.:1262780-97-1
Molecular Formula:C38H73N21O10S2
Molecular Weight:1048.25
Hs Code.:
Mol file:1262780-97-1.mol

Synonyms:Etelcalcetide

Suppliers and Price of Etelcalcetide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
Etelcalcetide
25mg
$ 520.00

ChemScene
Etelcalcetide
10mg
$ 260.00

ChemScene
Etelcalcetide
5mg
$ 138.00

ChemScene
Etelcalcetide
1mg
$ 55.00

Total 41 raw suppliers

Chemical Property of Etelcalcetide

Chemical Property:

PKA:2.01±0.10(Predicted)
PSA：608.31000
Density:1.58±0.1 g/cm3(Predicted)
LogP:1.67200

Purity/Quality:

99%, ^*data from raw suppliers

Etelcalcetide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Clinical Use Synthetic peptide calcimimetic agent:Treatment of secondary hyperparathyroidism in patients on haemodialysis
Drug interactions Potentially hazardous interactions with other drugs Avoid with cinacalcet.

Technology Process of Etelcalcetide

There total 14 articles about Etelcalcetide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 2799-07-7
S-trityl-L-cysteine

: Ac-D-Cys(Trt)-D-Ala-D-Arg-D-Arg-D-Arg-D-Ala-D-Arg-NH₂tetrahydrochloride

: 1262780-97-1
etelcalcetide

Guidance literature:: With hydrogenchloride; iodine; In methanol; water; pH=1.85;

Reference yield: 60.0%

: 1198791-73-9,177582-21-7
Fmoc-D-Cys (Mtt)-OH

: 76880-29-0
N-α-tert-butoxycarbonyl-S-(3-nitro-2-pyridylthio)-L-cysteine

: 108-24-7
acetic anhydride

: 35661-38-2,35661-39-3,79990-15-1,136132-75-7
N-(9-fluorenylmethoxycarbonyl)-D-alanine

: 187618-60-6
N-α-[(9H-fluoren-9-ylmethoxy)carbonyl]-N^G-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-D-arginine

: 1262780-97-1
etelcalcetide

Guidance literature:: N-α-[(9H-fluoren-9-ylmethoxy)carbonyl]-N^G-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-D-arginine; With 4-(2,4-dimethoxyphenyl-Fmoc-aminomethyl)phenoxy resin; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In 1-methyl-pyrrolidin-2-one; at 20 ℃; for 5h; rink amide resin

With piperidine; In 1-methyl-pyrrolidin-2-one; rink amide resin

Fmoc-D-Cys (Mtt)-OH; N-α-tert-butoxycarbonyl-S-(3-nitro-2-pyridylthio)-L-cysteine; acetic anhydride; N-(9-fluorenylmethoxycarbonyl)-D-alanine; N-α-[(9H-fluoren-9-ylmethoxy)carbonyl]-N^G-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-D-arginine; Further stages;