Technology Process of 1-Cyclopentene-1-carboxylicacid,4-amino-(9CI)
There total 18 articles about 1-Cyclopentene-1-carboxylicacid,4-amino-(9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
ethyl acetate;
for 4h;
DOI:10.1021/jm4006548
- Guidance literature:
-
Multi-step reaction with 9 steps
1: 43.7 g / N-bromosiccinimide / CCl4 / 2.5 h / Heating; Irradiation
2: liquid ammonia / diethyl ether / 1.33 h / -70 - -60 °C
3: HCl / 0.5 h
4: potassium carbonate / H2O / 1.) 5-10 deg C, 0.5 h, 2.) RT, 1 h
5: 260 mg / H2 / 10percent Pd/C / ethanol / 3 h / 3040 Torr
6: 6 M HCl / 3 h / Heating
7: 61 percent / 0.5 h / 160 °C
8: 45 percent / red phosphorus, bromine / 4 h / Heating
9: 48percent HBr / 16 h / Heating
With
hydrogenchloride; phosphorus; N-Bromosuccinimide; ammonia; hydrogen bromide; hydrogen; bromine; potassium carbonate;
palladium on activated charcoal;
In
tetrachloromethane; diethyl ether; ethanol; water;
DOI:10.1071/CH9800599
- Guidance literature:
-
Multi-step reaction with 8 steps
1: liquid ammonia / diethyl ether / 1.33 h / -70 - -60 °C
2: HCl / 0.5 h
3: potassium carbonate / H2O / 1.) 5-10 deg C, 0.5 h, 2.) RT, 1 h
4: 260 mg / H2 / 10percent Pd/C / ethanol / 3 h / 3040 Torr
5: 6 M HCl / 3 h / Heating
6: 61 percent / 0.5 h / 160 °C
7: 45 percent / red phosphorus, bromine / 4 h / Heating
8: 48percent HBr / 16 h / Heating
With
hydrogenchloride; phosphorus; ammonia; hydrogen bromide; hydrogen; bromine; potassium carbonate;
palladium on activated charcoal;
In
diethyl ether; ethanol; water;
DOI:10.1071/CH9800599
