(4R)-A(1)-Nor-2,3-seco-D:A-friedooleanane-2,3,24-trioic acid trimethyl ester

Base Information

• Chemical Name: (4R)-A(1)-Nor-2,3-seco-D:A-friedooleanane-2,3,24-trioic acid trimethyl ester
• CAS No.: 43230-22-4
• Molecular Formula: C32H52O6
• Molecular Weight: 532.75
• Mol file: 43230-22-4.mol

Synonyms:(4R)-A(1)-Nor-2,3-seco-D:A-friedooleanane-2,3,24-trioic acid trimethyl ester

Chemical Property of (4R)-A(1)-Nor-2,3-seco-D:A-friedooleanane-2,3,24-trioic acid trimethyl ester

Chemical Property:

• PSA: 78.90000
• LogP: 6.59320

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4R)-A(1)-Nor-2,3-seco-D:A-friedooleanane-2,3,24-trioic acid trimethyl ester

There total 4 articles about (4R)-A(1)-Nor-2,3-seco-D:A-friedooleanane-2,3,24-trioic acid trimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3-Dioxo-24-hydroxy-friedelan (43230-65-5) → (1S,2S,4aS,4bR,6aR,10aR,10bS,12aR)-2-((R)-1-Methoxycarbonyl-ethyl)-4b,6a,9,9,10b,12a-hexamethyl-octadecahydro-chrysene-1,2-dicarboxylic acid dimethyl ester (43230-22-4)

Guidance literature:

Multi-step reaction with 3 steps

1: CrO₃*2Py

2: KMnO₄

With potassium permanganate; dipyridine chromium trioxide;

DOI:10.1016/S0040-4020(01)83157-4

Reference yield:

1,3-dioxo-friedelan-24-al (35162-67-5) → (1S,2S,4aS,4bR,6aR,10aR,10bS,12aR)-2-((R)-1-Methoxycarbonyl-ethyl)-4b,6a,9,9,10b,12a-hexamethyl-octadecahydro-chrysene-1,2-dicarboxylic acid dimethyl ester (43230-22-4)

Guidance literature:

Multi-step reaction with 2 steps

1: KMnO₄

With potassium permanganate;

DOI:10.1016/S0040-4020(01)83157-4

Reference yield:

1.3-Dioxo-friedelan-24-carbonsaeure (43230-66-6) → (1S,2S,4aS,4bR,6aR,10aR,10bS,12aR)-2-((R)-1-Methoxycarbonyl-ethyl)-4b,6a,9,9,10b,12a-hexamethyl-octadecahydro-chrysene-1,2-dicarboxylic acid dimethyl ester (43230-22-4)

Guidance literature:

Multi-step reaction with 2 steps

1: KMnO₄

With potassium permanganate;

DOI:10.1016/S0040-4020(01)83157-4

upstream raw materials:

diazomethane

(1S,2S,4aS,4bR,6aR,10aR,10bS,12aR)-2-((R)-1-Carboxy-ethyl)-4b,6a,9,9,10b,12a-hexamethyl-octadecahydro-chrysene-1,2-dicarboxylic acid

1,3-Dioxo-24-hydroxy-friedelan

1,3-dioxo-friedelan-24-al