LANTHIONINE; DL-(RG)

Base Information

• Chemical Name: LANTHIONINE; DL-(RG)
• CAS No.: 496-98-0
• Molecular Formula: C6H12N2O4S
• Molecular Weight: 208.23
• Mol file: 496-98-0.mol

Synonyms:LANTHIONINE; DL-(RG);Lanthionine (DL- and meso- mixture);DL-andmeso-mixture;(2R)-2-amino-3-[(2R)-2-amino-3-hydroxy-3-oxopropyl]sulfanylpropanoic acid;(2R)-2-amino-3-[[(2R)-2-amino-3-hydroxy-3-keto-propyl]thio]propionic acid;(2R)-2-azanyl-3-[(2R)-2-azanyl-3-hydroxy-3-oxo-propyl]sulfanyl-propanoic acid;3,3'-Thiodialanine 3,3'-Thiobis(2-aminopropionic Acid);Lanthionine 

Chemical Property of LANTHIONINE; DL-(RG)

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of LANTHIONINE; DL-(RG)

There total 40 articles about LANTHIONINE; DL-(RG) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

N,N'-bis(trifluoroacetyl)-L-lanthionine dimethyl ester (26527-25-3) → D,L-Lanthionine (922-55-4,496-98-0)

Guidance literature:

N,N'-bis(trifluoroacetyl)-L-lanthionine dimethyl ester; With sodium hydroxide; In 1,4-dioxane; at 0 - 5 ℃;

With hydrogenchloride; In 1,4-dioxane; water; pH=6;

DOI:10.1016/j.tet.2010.03.091

Reference yield: 55.0%

(R)-3-[(R)-2-Methoxycarbonyl-2-(2,2,2-trifluoro-acetylamino)-ethylsulfanyl]-2-(2,2,2-trifluoro-acetylamino)-propionic acid methyl ester (26527-25-3) → D,L-Lanthionine (922-55-4,496-98-0)

Guidance literature:

With water; sodium hydroxide; In tetrahydrofuran; at 0 ℃; for 1h; Inert atmosphere;

DOI:10.1002/asia.201801031

Reference yield:

→ meso-lanthionine (922-56-5,496-98-0) + racem.-bis-(2-amino-2-carboxy-ethyl)-sulfide (3183-08-2,496-98-0)

Guidance literature:

With 1,4-dioxane; hydrogenchloride; at 140 ℃;

upstream raw materials:

3-chloro-DL-alanine methyl ester

L-Cysteine

N-Acetamidoacrylic acid

water

Downstream raw materials:

N.N'-bis-benzyloxycarbonyl-meso-lanthionine

N-benzyloxycarbonyl-L-cysteine

N,N'-dibenzoyl-L-lanthionine

N,N'-dibenzoyl-D-lanthionine