BOSENTAN-D4

Base Information

Chemical Name:BOSENTAN-D4
CAS No.:1065472-77-6
Molecular Formula:C27H25D4N5O6S
Molecular Weight:555.591
Hs Code.:

Synonyms:BOSENTAN-D4;4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy-d4)-5-(2-methoxyphenoxy)[2,2bipyrimidin]-4-yl]benzenesulfonamide;Actelion-d4;p-tert-Butyl-N-[6-(2-hydroxyethoxy-d4)-5- (o-Methoxyphenoxy)-2-(2-pyriMidinyl)-4-pyriMidinyl]benzenesulfonaMide;Ro 47-0203/039-d4;Ro 47-0203-d4;Tracleer-d4

Suppliers and Price of BOSENTAN-D4

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Bosentan-d4
1mg
$ 446.00

TRC
Bosentan-d4
2.5mg
$ 155.00

TRC
Bosentan-d4
25mg
$ 1030.00

Cayman Chemical
Bosentan-d4 ≥99% deuterated forms (d1-d4)
5mg
$ 225.00

Cayman Chemical
Bosentan-d4 ≥99% deuterated forms (d1-d4)
25mg
$ 795.00

American Custom Chemicals Corporation
BOSENTAN-D4 95.00%
1MG
$ 739.20

American Custom Chemicals Corporation
BOSENTAN-D4 95.00%
10MG
$ 1871.10

AK Scientific
Bosentan-d4
25mg
$ 1173.00

Total 5 raw suppliers

Chemical Property of BOSENTAN-D4

Chemical Property:

Melting Point:97-104°C
PSA：154.03000
LogP:5.35770
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Methanol (Very Slightly)

Purity/Quality:

> 95% ^*data from raw suppliers

Bosentan-d4 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses BOSENTAN-D4 is a labeled mixed endothelin receptor antagonist. Used as a vasodilator Labelled Bosentan (B675900). A mixed endothelin receptor antagonist. Used as a vasodilator. Antihypertensive.

Technology Process of BOSENTAN-D4

There total 1 articles about BOSENTAN-D4 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 15054-86-1
ethylene glycol-d₆

: 150727-06-3
4-tert-butyl-N-(6-chloro-5-(2-methoxyphenoxy)2,2'-bipyrimidin-4-yl)benzene sulfonamide

: 1065472-77-6
d4-4-tert-butyl-N-[6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide

Guidance literature:: ethylene glycol-d₆; 4-tert-butyl-N-(6-chloro-5-(2-methoxyphenoxy)2,2'-bipyrimidin-4-yl)benzene sulfonamide; With sodium; In 1,2-dimethoxyethane; at 100 ℃; for 16h;

With water; tartaric acid; pH=3;