Benzoic acid, 4-amino-2,5-difluoro-3-methyl-, methyl ester (9CI)

Base Information

Chemical Name:Benzoic acid, 4-amino-2,5-difluoro-3-methyl-, methyl ester (9CI)
CAS No.:208166-53-4
Molecular Formula:C9H9F2NO2
Molecular Weight:201.173
Hs Code.:
Mol file:208166-53-4.mol

Synonyms:Benzoic acid, 4-amino-2,5-difluoro-3-methyl-, methyl ester (9CI)

Suppliers and Price of Benzoic acid, 4-amino-2,5-difluoro-3-methyl-, methyl ester (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Benzoic acid, 4-amino-2,5-difluoro-3-methyl-, methyl ester (9CI)

Chemical Property:

Boiling Point:322.2±42.0 °C(Predicted)
PKA:-0.09±0.10(Predicted)
PSA：52.32000
Density:1.303±0.06 g/cm3(Predicted)
LogP:2.22320

Purity/Quality:: 99%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 4-amino-2,5-difluoro-3-methyl-, methyl ester (9CI)

There total 4 articles about Benzoic acid, 4-amino-2,5-difluoro-3-methyl-, methyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.8%

: 479090-47-6
methyl 2,4,5-trifluoro-3-methylbenzoate

: 208166-53-4
methyl 4-amino-2,5-difluoro-3-methylbenzoate

Guidance literature:: methyl 2,4,5-trifluoro-3-methylbenzoate; With triethylamine; benzylamine; In dimethyl sulfoxide; at 100 ℃; for 20h;

With palladium 10% on activated carbon; hydrogen; In methanol; dimethyl sulfoxide; at 20 ℃; under 760.051 Torr;

Reference yield:

: 479090-48-7
4-benzylamino-2,5-difluoro-3-methylbenzoic acid methyl ester

: 208166-53-4
methyl 4-amino-2,5-difluoro-3-methylbenzoate

Guidance literature:: With ammonium formate; palladium; In methanol;

Reference yield:

: 112822-85-2
3-methyl-2,4,5-trifluorobenzoic acid

: 208166-53-4
methyl 4-amino-2,5-difluoro-3-methylbenzoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sulfuric acid / 50 °C

2.1: benzylamine; triethylamine / dimethyl sulfoxide / 20 h / 100 °C

2.2: 20 °C / 760.05 Torr

With sulfuric acid; triethylamine; benzylamine; In dimethyl sulfoxide;