(2Z)-2-hydroxyimino-2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]-1,3-thiazol-4-yl]acetic Acid

Base Information

Chemical Name:(2Z)-2-hydroxyimino-2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]-1,3-thiazol-4-yl]acetic Acid
CAS No.:140128-26-3
Molecular Formula:C10H13N3O5S
Molecular Weight:287.29
Hs Code.:
DSSTox Substance ID:DTXSID801130410
Mol file:140128-26-3.mol

Synonyms:140128-26-3;(2Z)-2-hydroxyimino-2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]-1,3-thiazol-4-yl]acetic Acid;SCHEMBL6051484;DTXSID801130410;EN300-20070305;(alphaZ)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]-alpha-(hydroxyimino)-4-thiazoleacetic acid;2-(2-{[(tert-butoxy)carbonyl]amino}-1,3-thiazol-4-yl)-2-(N-hydroxyimino)acetic acid

Suppliers and Price of (2Z)-2-hydroxyimino-2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]-1,3-thiazol-4-yl]acetic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of (2Z)-2-hydroxyimino-2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]-1,3-thiazol-4-yl]acetic Acid

Chemical Property:

PSA：149.35000
LogP:1.82600
XLogP3:2.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:5
Exact Mass:287.05759170
Heavy Atom Count:19
Complexity:393

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=NC(=CS1)C(=NO)C(=O)O
Isomeric SMILES:CC(C)(C)OC(=O)NC1=NC(=CS1)/C(=N/O)/C(=O)O

Technology Process of (2Z)-2-hydroxyimino-2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]-1,3-thiazol-4-yl]acetic Acid

There total 3 articles about (2Z)-2-hydroxyimino-2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]-1,3-thiazol-4-yl]acetic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 186091-52-1
(2-tert-butoxycarbonylamino-thiazol-4-yl)-hydroxyimino-acetic acid ethyl ester

: 140128-26-3
(2-tert-butoxycarbonylamino-thiazol-4-yl)-hydroxyimino-acetic acid

Guidance literature:: With sodium hydroxide; In ethanol;
DOI:10.1016/S0960-894X(00)00425-X

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 140128-26-3
(2-tert-butoxycarbonylamino-thiazol-4-yl)-hydroxyimino-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: DMAP / CH₂Cl₂

2: aq. NaOH / ethanol

With dmap; sodium hydroxide; In ethanol; dichloromethane; 1: Acylation / 2: Hydrolysis;
DOI:10.1016/S0960-894X(00)00425-X

Reference yield:

: (2-Amino-thiazol-4-yl)-[(Z)-hydroxyimino]-acetic acid ethyl ester; hydrochloride

: 140128-26-3
(2-tert-butoxycarbonylamino-thiazol-4-yl)-hydroxyimino-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: DMAP / CH₂Cl₂

2: aq. NaOH / ethanol

With dmap; sodium hydroxide; In ethanol; dichloromethane; 1: Acylation / 2: Hydrolysis;
DOI:10.1016/S0960-894X(00)00425-X