2,3,4-TRI-O-ACETYL-1-BROMO-1-DEOXY-BETA-D-XYLOPYRANOSYL CYANIDE

Base Information

• Chemical Name: 2,3,4-TRI-O-ACETYL-1-BROMO-1-DEOXY-BETA-D-XYLOPYRANOSYL CYANIDE
• CAS No.: 83497-43-2
• Molecular Formula: C₁₂H₁₄BrNO₇
• Molecular Weight: 364.15
• Hs Code.: 2932999099
• Mol file: 83497-43-2.mol

Synonyms:2,3,4-TRI-O-ACETYL-1-BROMO-1-DEOXY-BETA-D-XYLOPYRANOSYL CYANIDE;2,3,4-TRI-O-ACETYL-1-BROMO-1-DEOXY-SS-D-XYLOPYRANOSYL CYANIDE

Chemical Property of 2,3,4-TRI-O-ACETYL-1-BROMO-1-DEOXY-BETA-D-XYLOPYRANOSYL CYANIDE

Chemical Property:

• PSA: 111.92000
• LogP: 0.42648

Purity/Quality:

97% ^*data from raw suppliers

2,3,4-TRI-O-ACETYL-1-BROMO-1-DEOXY-BETA-D-XYLOPYRANOSYL CYANIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3,4-TRI-O-ACETYL-1-BROMO-1-DEOXY-BETA-D-XYLOPYRANOSYL CYANIDE

There total 2 articles about 2,3,4-TRI-O-ACETYL-1-BROMO-1-DEOXY-BETA-D-XYLOPYRANOSYL CYANIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

1-deoxy-2,3,4,6-tetra-O-acetyl-β-D-xylopyranosyl cyanide (52443-06-8) → 2,3,4-tri-O-acetyl-1-deoxy-1-bromo-β-D-xylopyranosyl cyanide (83497-43-2)

Guidance literature:

With N-Bromosuccinimide; Perbenzoic acid; In tetrachloromethane; Heating;

DOI:10.1016/S0008-6215(00)80746-6

Reference yield:

1-deoxy-2,3,4,6-tetra-O-acetyl-β-D-xylopyranosyl cyanide (52443-06-8) → 2,3,4-tri-O-acetyl-1-deoxy-1-bromo-β-D-xylopyranosyl cyanide (83497-43-2) + Acetic acid (2S,3R,4S,5R)-4,5-diacetoxy-2-bromo-2-cyano-tetrahydro-pyran-3-yl ester (89158-10-1)

Guidance literature:

With N-Bromosuccinimide; Perbenzoic acid; In tetrachloromethane; for 0.666667h; Heating;

DOI:10.1016/0008-6215(83)88354-2

Reference yield: 38.0%

2,3,4-tri-O-acetyl-1-deoxy-1-bromo-β-D-xylopyranosyl cyanide (83497-43-2) → 2,3,4-tri-O-acetyl-1-deoxy-1-fluoro-β-D-xylopyranosyl cyanide

Guidance literature:

With silver tetrafluoroborate; In toluene; for 168h; Ambient temperature;

DOI:10.1016/S0040-4020(98)00813-8

upstream raw materials:

1-deoxy-2,3,4,6-tetra-O-acetyl-β-D-xylopyranosyl cyanide

Downstream raw materials:

1-deoxy-2,3,4,6-tetra-O-acetyl-β-D-xylopyranosyl cyanide

4,5-Di-O-acetyl-2,6-anhydro-3-deoxy-D-threo-hex-2-enononitrile

2,3,4-tri-O-acetyl-α-D-xylopyranosyl cyanide

(1R)-2,3,4-tri-O-acetyl-1-azido-D-xylopyranosyl cyanide