4-Chloro-5-iodo-2-methylpyrimidine

Base Information

Chemical Name:4-Chloro-5-iodo-2-methylpyrimidine
CAS No.:111079-17-5
Molecular Formula:C₅H₄ClIN₂
Molecular Weight:254.458
Hs Code.:
European Community (EC) Number:867-706-6
DSSTox Substance ID:DTXSID10545573
Wikidata:Q82423114
Mol file:111079-17-5.mol

Synonyms:4-Chloro-5-iodo-2-methylpyrimidine;111079-17-5;4-CHLORO-5-IODO-2-METHYL-PYRIMIDINE;Pyrimidine, 4-chloro-5-iodo-2-methyl-;SCHEMBL3710693;DTXSID10545573;AMY27440;MFCD09746250;AKOS015151551;SB59072;AS-50178;CS-0045724;EN300-117206;O11217;4-chloro-5-iodo-2-methyl-pyrimidine, AldrichCPR;Z1269236794

Suppliers and Price of 4-Chloro-5-iodo-2-methylpyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Chloro-5-iodo-2-methylpyrimidine 95+%
250mg
$ 232.00

Crysdot
4-Chloro-5-iodo-2-methylpyrimidine 95+%
1g
$ 580.00

Chemenu
4-Chloro-5-iodo-2-methylpyrimidine 95%
1g
$ 542.00

American Custom Chemicals Corporation
4-CHLORO-5-IODO-2-METHYLPYRIMIDINE 95.00%
5MG
$ 497.56

Abosyn
4-Chloro-5-iodo-2-methyl-pyrimidine >95%
5g
$ 870.00

Abosyn
4-Chloro-5-iodo-2-methyl-pyrimidine >95%
1g
$ 249.00

Total 5 raw suppliers

Chemical Property of 4-Chloro-5-iodo-2-methylpyrimidine

Chemical Property:

PSA：25.78000
LogP:2.04300
Storage Temp.:Keep in dark place,Sealed in dry,Store in freezer, under -20°C
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:253.91077
Heavy Atom Count:9
Complexity:101

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-5-iodo-2-methylpyrimidine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC=C(C(=N1)Cl)I

Technology Process of 4-Chloro-5-iodo-2-methylpyrimidine

There total 2 articles about 4-Chloro-5-iodo-2-methylpyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 111079-41-5
5-iodo-2-methyl-4(3H)-pyrimidinone

: 111079-17-5
2-methyl-4-chloro-5-iodopyrimidine

Guidance literature:: With trichlorophosphate; Heating;

Reference yield:

: 19875-04-8,127892-80-2
2-methyl-3H-pyrimidin-4-one

: 111079-17-5
2-methyl-4-chloro-5-iodopyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 46 percent / I₂ / HNO₃ / 6 h / 80 °C

2: 82 percent / POCl₃ / Heating

With iodine; trichlorophosphate; In nitric acid;

Reference yield:

: 111079-17-5
2-methyl-4-chloro-5-iodopyrimidine

: 56844-01-0
2-methyl-thieno[2,3-d]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / Pd(PPh₃)2Cl₂, CuI, Et₃N / 12 h / 80 °C

2: 73 percent / NaOEt, H₂S / ethanol / 1.5 h / Heating

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; hydrogen sulfide; sodium ethanolate; triethylamine; In ethanol;