1-Cyclohexylmethyl-5-oxo-pyrrolidine-3-carboxylic acid

Base Information

Chemical Name:1-Cyclohexylmethyl-5-oxo-pyrrolidine-3-carboxylic acid
CAS No.:304859-16-3
Molecular Formula:C₁₂H₁₉NO₃
Molecular Weight:225.288
Hs Code.:2933790090
Mol file:304859-16-3.mol

Synonyms:1-Cyclohexylmethyl-5-oxo-pyrrolidine-3-carboxylic acid;304859-16-3;1-(Cyclohexylmethyl)-5-oxopyrrolidine-3-carboxylic acid;SCHEMBL7459273;AKOS000302244;AKOS016340889;BS-4331;BB 0218100;CS-0117046;1-Cyclohexylmethyl-5-oxo-pyrrolidine-3-carboxylicacid

Suppliers and Price of 1-Cyclohexylmethyl-5-oxo-pyrrolidine-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-Cyclohexylmethyl-5-oxo-pyrrolidine-3-carboxylic acid
1g
$ 385.00

Matrix Scientific
1-Cyclohexylmethyl-5-oxo-pyrrolidine-3-carboxylic acid
500mg
$ 250.00

American Custom Chemicals Corporation
1-(CYCLOHEXYLMETHYL)-5-OXOPYRROLIDINE-3-CARBOXYLIC ACID 95.00%
500MG
$ 796.95

Total 3 raw suppliers

Chemical Property of 1-Cyclohexylmethyl-5-oxo-pyrrolidine-3-carboxylic acid

Chemical Property:

PSA：57.61000
LogP:1.43770
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:225.13649347
Heavy Atom Count:16
Complexity:284

Purity/Quality:

98%min ^*data from raw suppliers

1-Cyclohexylmethyl-5-oxo-pyrrolidine-3-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(CC1)CN2CC(CC2=O)C(=O)O

Technology Process of 1-Cyclohexylmethyl-5-oxo-pyrrolidine-3-carboxylic acid

There total 1 articles about 1-Cyclohexylmethyl-5-oxo-pyrrolidine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 97-65-4,25119-64-6
2-methylenesuccinic acid

: 3218-02-8
cyclohexylmethylamine

: 304859-16-3
1-(cyclohexylmethyl)-5-oxo-3-pyrrolidinecarboxylic acid

Guidance literature:: DOI:10.1248/cpb.52.63

Reference yield:

: 304859-16-3
1-(cyclohexylmethyl)-5-oxo-3-pyrrolidinecarboxylic acid

: 1-cyclohexylmethyl-5-oxo-pyrrolidine-3-carbonyl chloride

Guidance literature:: With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 0 - 20 ℃;
DOI:10.1248/cpb.52.63

Reference yield:

: 304859-16-3
1-(cyclohexylmethyl)-5-oxo-3-pyrrolidinecarboxylic acid

: N-[3-(4-benzylpiperidin-1-yl)propyl]-1-(cyclohexylmethyl)-5-oxo-N-phenylpyrrolidine-3-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: (COCl)2; DMF / CH₂Cl₂ / 0 - 20 °C

2: Et₃N / CH₂Cl₂ / -20 - 0 °C

With oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1248/cpb.52.63