O-tert·Butyl-trans-4-hydroxy-L-prolinetert·butyl

Base Information

Chemical Name:O-tert·Butyl-trans-4-hydroxy-L-prolinetert·butyl
CAS No.:93527-54-9
Molecular Formula:C₁₃H₂₅NO₃
Molecular Weight:243.346
Hs Code.:

Synonyms:O-tert·Butyl-trans-4-hydroxy-L-prolinetert·butyl

Suppliers and Price of O-tert·Butyl-trans-4-hydroxy-L-prolinetert·butyl

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(2S,4R)-tert-Butyl4-(tert-butoxy)pyrrolidine-2-carboxylate 97%
5g
$ 698.00

Total 10 raw suppliers

Chemical Property of O-tert·Butyl-trans-4-hydroxy-L-prolinetert·butyl

Chemical Property:

Boiling Point:76-78 °C(Press: 0.1 Torr)
PKA:7.38±0.10(Predicted)
PSA：47.56000
Density:0.99±0.1 g/cm3(Predicted)
LogP:2.20250

Purity/Quality:

97% ^*data from raw suppliers

(2S,4R)-tert-Butyl4-(tert-butoxy)pyrrolidine-2-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of O-tert·Butyl-trans-4-hydroxy-L-prolinetert·butyl

There total 3 articles about O-tert·Butyl-trans-4-hydroxy-L-prolinetert·butyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 96167-96-3
Z-L-Hyp(tBu)-OtBu

: 93527-54-9
H-L-Hyp(tBu)-OtBu

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 5h;

Reference yield:

: 4-tert-butoxy-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-tert-butyl ester

: 93527-54-9
Hyp(Ot-Bu)Ot-Bu

Guidance literature:: With hydrogen; palladium on activated charcoal;
DOI:10.1016/S0040-4039(03)00021-2

Reference yield:

: 13504-85-3,13504-86-4,91958-67-7,99095-63-3,130930-25-5
Z-L-Hyp-OH

: 93527-54-9
H-L-Hyp(tBu)-OtBu

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / conc.H₂SO₄ / CH₂Cl₂ / 50 h / 20 °C

2: 70 percent / H₂ / Pd/C (5percent) / methanol / 5 h

With sulfuric acid; hydrogen; palladium on activated charcoal; In methanol; dichloromethane;