delta-12-Pgd2

Base Information

Chemical Name:delta-12-Pgd2
CAS No.:64072-89-5
Molecular Formula:C₂₀H₃₂O₅
Molecular Weight:352.471
Hs Code.:
DSSTox Substance ID:DTXSID401348009
Nikkaji Number:J71.098I
Wikidata:Q76293732
Metabolomics Workbench ID:2456
ChEMBL ID:CHEMBL163786

Synonyms:delta-12-Pgd2;delta12-Prostaglandin D2;64072-89-5;delta(sup 12)-PGD2;delta(sup 12)-Prostaglandin D2;BRN 6071542;(5Z,9-alpha,12E,15S)-9,15-Dihydroxy-11-oxoprosta-5,12-dien-1-oic acid;(Z)-7-[(1R,2E,5S)-5-hydroxy-2-[(3S)-3-hydroxyoctylidene]-3-oxocyclopentyl]hept-5-enoic acid;Prosta-5,12-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, (5Z,9-alpha,12E,15S)-;9S,15S-dihydroxy-11-oxo-5Z,12E-prostadienoic acid;.DELTA.12-Prostaglandin D2;Delta 12-Prostaglandin D2;CHEMBL163786;SCHEMBL23352598;DTXSID401348009;HMS3648O03;LMFA03010101;LS-125821;SR-01000946247;SR-01000946247-1;Prosta-5,12-dien-1-oicacid,9,15-dihydroxy-11-oxo-,(5z,9a,12e,15s)-

Suppliers and Price of delta-12-Pgd2

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
Δ12-Prostaglandin-d2 >98%
5 mg
$ 1200.00

Medical Isotopes, Inc.
Δ12-Prostaglandin-d2 >98%
0.5 mg
$ 790.00

Cayman Chemical
Δ12-Prostaglandin D2 ≥98%
10mg
$ 575.00

Cayman Chemical
Δ12-Prostaglandin D2 ≥98%
1mg
$ 79.00

Cayman Chemical
Δ12-Prostaglandin D2 ≥98%
500μg
$ 42.00

Cayman Chemical
Δ12-Prostaglandin D2 ≥98%
5mg
$ 330.00

American Custom Chemicals Corporation
DELTA12-PROSTAGLANDIN D2 95.00%
5MG
$ 500.41

American Custom Chemicals Corporation
DELTA12-PROSTAGLANDIN D2 95.00%
1MG
$ 194.25

AK Scientific
9alpha,15S-Dihydroxy-11-oxo-prosta-5Z,12E-dien-1-oicacid
5mg
$ 510.00

Total 4 raw suppliers

Chemical Property of delta-12-Pgd2

Chemical Property:

Vapor Pressure:2.26E-15mmHg at 25°C
Boiling Point:570.1 ºC at 760 mmHg
Flash Point:312.6 ºC
PSA：94.83000
Density:1.156 g/cm3
LogP:3.39520
XLogP3:2.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:12
Exact Mass:352.22497412
Heavy Atom Count:25
Complexity:481

Purity/Quality:

99% ^*data from raw suppliers

Δ12-Prostaglandin-d2 >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCC(CC=C1C(C(CC1=O)O)CC=CCCCC(=O)O)O
Isomeric SMILES:CCCCC[C@@H](C/C=C/1\[C@H]([C@H](CC1=O)O)C/C=C\CCCC(=O)O)O
Description Prostaglandin D2 (PGD2) is one of the five primary enzymatic prostaglandins derived directly from PGH2. PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and basophils by a second, hematopoietic-type PGD synthase. PGD2 is chemically unstable, and its use and analysis is complicated by its short in vivo half-life. Δ12-PGD2 is one of the initial chemical decomposition products of PGD2. Δ12-PGD2 is an intermediate in the pathway leading to Δ12-PGJ2, which is a cyclopentenone prostaglandin with antimitotic and carcinogenic activities. The metabolism of Δ12-PGD2 involves addition of thiol nucleophiles, as is the case with the majority of cyclopentenone prostaglandins.

Technology Process of delta-12-Pgd2

There total 3 articles about delta-12-Pgd2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%