2-Thiazolecarboxaldehyde, 5-methyl-, oxime

Base Information

• Chemical Name: 2-Thiazolecarboxaldehyde, 5-methyl-, oxime
• CAS No.: 454483-82-0
• Molecular Formula: C₅H₆N₂OS
• Molecular Weight: 142.181
• Mol file: 454483-82-0.mol

Synonyms:2-Thiazolecarboxaldehyde, 5-methyl-, oxime

Chemical Property of 2-Thiazolecarboxaldehyde, 5-methyl-, oxime

Chemical Property:

• Boiling Point: 310.3±35.0 °C(Predicted)
• PKA: 9.95±0.10(Predicted)
• PSA: 73.72000
• Density: 1.35±0.1 g/cm3(Predicted)
• LogP: 1.25960

Purity/Quality:

5-methyl-2-Thiazolecarboxaldehydeoxime 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Thiazolecarboxaldehyde, 5-methyl-, oxime

There total 1 articles about 2-Thiazolecarboxaldehyde, 5-methyl-, oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-methyl-1,3-thiazole-2-carbaldehyde (13838-78-3) → 5-methyl-thiazole-2-carbaldehyde oxime (454483-82-0)

Guidance literature:

With 4-methyl-morpholine; hydroxylamine hydrochloride; In methanol; at 20 ℃; for 22h;

DOI:10.1016/S0960-894X(02)00129-4

Reference yield: 92.0%

5-methyl-thiazole-2-carbaldehyde oxime (454483-82-0) → 5-methyl-thiazole-2-carbonitrile (100516-71-0)

Guidance literature:

With 1,1'-carbonyldiimidazole; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1016/S0960-894X(02)00129-4

upstream raw materials:

5-methyl-1,3-thiazole-2-carbaldehyde

Downstream raw materials:

5-methyl-thiazole-2-carbonitrile