2-Benzofuranglyoxylaldehyde

Base Information

• Chemical Name: 2-Benzofuranglyoxylaldehyde
• CAS No.: 40749-31-3
• Molecular Formula: C10H6O3
• Molecular Weight: 174.156
• Hs Code.: 2932209090
• Mol file: 40749-31-3.mol

Synonyms:2-Benzofuranglyoxylaldehyde;2-(benzofuran-2-yl)-2-oxoacetaldehyde

Chemical Property of 2-Benzofuranglyoxylaldehyde

Chemical Property:

• Vapor Pressure: 0.00551mmHg at 25°C
• Boiling Point: 274.1°C at 760 mmHg
• Flash Point: 122.6°C
• PSA: 47.28000
• Density: 1.288g/cm³
• LogP: 1.81440

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Benzofuranglyoxylaldehyde

There total 4 articles about 2-Benzofuranglyoxylaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(benzo[b]furan-2-yl)ethanone (1646-26-0) → benzofuran-2-ylglyoxal (40749-31-3)

Guidance literature:

With 1,4-dioxane; selenium(IV) oxide;

Reference yield:

1,4-dioxane (123-91-1,28347-88-8,28347-91-3,39449-24-6,54841-74-6) + 1-(benzo[b]furan-2-yl)ethanone (1646-26-0) → benzofuran-2-ylglyoxal (40749-31-3)

Guidance literature:

With selenium(IV) oxide; In N-methyl-acetamide; water;

Reference yield:

2-benzofuranyl iodomethyl ketone → benzofuran-2-ylglyoxal (40749-31-3)

Guidance literature:

With iodine; potassium hydroxide; In water; dimethyl sulfoxide; at 100 ℃;

DOI:10.1021/jo302754c

upstream raw materials:

1-(benzo[b]furan-2-yl)ethanone

2-methyl-benzyl alcohol

1,4-dioxane

Downstream raw materials:

Benzofuran-2-carboxylic acid

N-[2-(4-methylphenyl)-1,1-dimethylethyl]-2-(2-benzofuranyl)-2-hydroxyethanamine

benzofuran-2-yl-phenyl-ethanedione-bis-phenylhydrazone

benzofuran-2-yl-glyoxal-bis-phenylhydrazone

Refernces

• 1、 Liu, Cong,Dai, Rong J.,Yao, Guo W.,Deng, Yu L.. "Synthesis of 2-aroyl-(4 or 5)-aryl-1H-imidazoles and 2-hydroxy-3,6-diaryl- pyrazines via a cascade process". . p. 146 - 163. Retrieved 2014/04/17.
• 2、 Starke, Ines,Sarodnick, Gerhard,Ovcharenko, Vladimir V.,Pihlaja, Kalevi,Kleinpeter, Erich. "Quinoxalines. Part 13: Synthesis and mass spectrometric study of aryloxymethylquinoxalines and benzo[b]furylquinoxalines". . p. 6063 - 6078. Retrieved 2007/10/03.