2,5,8-Tri-tert-butyl-5,8-dihydro-2H-dipyrrolo[3,4-e:3',4'-g]isoindole

Base Information

Chemical Name:2,5,8-Tri-tert-butyl-5,8-dihydro-2H-dipyrrolo[3,4-e:3',4'-g]isoindole
CAS No.:118644-10-3
Molecular Formula:C24H33N3
Molecular Weight:363.54
Hs Code.:
DSSTox Substance ID:DTXSID90556501
Wikidata:Q82438064
Mol file:118644-10-3.mol

Synonyms:118644-10-3;2,5,8-Tri-tert-butyl-5,8-dihydro-2H-dipyrrolo[3,4-e:3',4'-g]isoindole;4,9,14-Tritert-butyl-4,9,14-triazatetracyclo[10.3.0.02,6.07,11]pentadeca-1(15),2,5,7,10,12-hexaene;DTXSID90556501

Suppliers and Price of 2,5,8-Tri-tert-butyl-5,8-dihydro-2H-dipyrrolo[3,4-e:3',4'-g]isoindole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2,5,8-Tri-tert-butyl-5,8-dihydro-2H-dipyrrolo[3,4-e:3',4'-g]isoindole

Chemical Property:

PSA：14.79000
LogP:6.81570
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:3
Exact Mass:363.267448065
Heavy Atom Count:27
Complexity:453

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)N1C=C2C3=CN(C=C3C4=CN(C=C4C2=C1)C(C)(C)C)C(C)(C)C

Technology Process of 2,5,8-Tri-tert-butyl-5,8-dihydro-2H-dipyrrolo[3,4-e:3',4'-g]isoindole

There total 5 articles about 2,5,8-Tri-tert-butyl-5,8-dihydro-2H-dipyrrolo[3,4-e:3',4'-g]isoindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 118644-12-5,118712-90-6
2,5,8-Tri-tert-butyl-2,3,4,5,6,7,8,9-octahydro-2H-benzo<1,2-c:3,4-c':5,6-c>tripyrrol-2,5,8-trioxid

: 118644-10-3
2,5,8-tri-tert-butylbenzo[1,2-c:3,4-c':5,6-c'']tripyrrole

Guidance literature:: With acetic anhydride; triethylamine; In chloroform; 1.) 0 deg C, 30 min, 2.) r. t., 60 min;

Reference yield:

: 87-85-4
Hexamethylbenzene

: 118644-10-3
2,5,8-tri-tert-butylbenzo[1,2-c:3,4-c':5,6-c'']tripyrrole

Guidance literature:: Multi-step reaction with 4 steps

1: 95 percent / Br₂ / various solvent(s) / 1.) reflux, 1 h, 2.) r. t., 18 h

2: 53 percent / ethyl-N,N-diisopropylamine / CHCl₃ / 44 h / Heating

3: 70 percent / 30percent H₂O₂ / methanol / 168 h / Ambient temperature

4: 53 percent / Et₃N, Ac₂O / CHCl₃ / 1.) 0 deg C, 30 min, 2.) r. t., 60 min

With dihydrogen peroxide; bromine; acetic anhydride; triethylamine; N-ethyl-N,N-diisopropylamine; In methanol; chloroform;

Reference yield:

: 118644-11-4
2,5,8-Tri-tert-butyl-2,3,4,5,6,7,8,9-octahydro-2H-benzo<1,2-c:3,4-c':5,6-c>tripyrrol

: 118644-10-3
2,5,8-tri-tert-butylbenzo[1,2-c:3,4-c':5,6-c'']tripyrrole

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / 30percent H₂O₂ / methanol / 168 h / Ambient temperature

2: 53 percent / Et₃N, Ac₂O / CHCl₃ / 1.) 0 deg C, 30 min, 2.) r. t., 60 min

With dihydrogen peroxide; acetic anhydride; triethylamine; In methanol; chloroform;