4-hydroxypiperidine-4-carboxylic Acid

Base Information

Chemical Name:4-hydroxypiperidine-4-carboxylic Acid
CAS No.:50289-06-0
Molecular Formula:C6H11NO3
Molecular Weight:145.158
Hs Code.:2933399090
DSSTox Substance ID:DTXSID10403285
Mol file:50289-06-0.mol

Synonyms:4-hydroxypiperidine-4-carboxylic Acid;50289-06-0;4-hydroxy-4-piperidinecarboxylic acid;MFCD00956083;4-HYDROXY-PIPERIDINE-4-CARBOXYLIC ACID;SCHEMBL1282200;DTXSID10403285;FKKPSFIMIQSISK-UHFFFAOYSA-N;4-hydroxypiperidine-4-carboxylicAcid;AKOS010488532;SB41449;AS-48317;SY240320;CS-0111716;FT-0755579;EN300-127656;F30328

Suppliers and Price of 4-hydroxypiperidine-4-carboxylic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Hydroxypiperidine-4-carboxylicacid 95+%
10g
$ 2480.00

Crysdot
4-Hydroxypiperidine-4-carboxylicacid 95+%
5g
$ 1488.00

Crysdot
4-Hydroxypiperidine-4-carboxylicacid 95+%
1g
$ 495.00

Chemenu
4-hydroxypiperidine-4-carboxylicacid 95%
1g
$ 468.00

Chemenu
4-hydroxypiperidine-4-carboxylicacid 95%
5g
$ 1403.00

Chemenu
4-hydroxypiperidine-4-carboxylicacid 95%
10g
$ 2338.00

American Custom Chemicals Corporation
4-HYDROXY-4-PIPERIDINECARBOXYLIC ACID 95.00%
5MG
$ 499.08

Alichem
4-Hydroxypiperidine-4-carboxylicacid
25g
$ 6416.55

Alichem
4-Hydroxypiperidine-4-carboxylicacid
10g
$ 3599.64

Alichem
4-Hydroxypiperidine-4-carboxylicacid
5g
$ 2472.98

Total 10 raw suppliers

Chemical Property of 4-hydroxypiperidine-4-carboxylic Acid

Chemical Property:

PSA：69.56000
LogP:-0.48570
Storage Temp.:2-8°C(protect from light)
XLogP3:-3.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:145.07389321
Heavy Atom Count:10
Complexity:140

Purity/Quality:

NLT 98% ^*data from raw suppliers

4-Hydroxypiperidine-4-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCCC1(C(=O)O)O

Technology Process of 4-hydroxypiperidine-4-carboxylic Acid

There total 4 articles about 4-hydroxypiperidine-4-carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 59119-18-5
1-benzyl-4-hydroxypiperidine-4-carboxylic acid

: 50289-06-0
4-hydroxypiperidine-4-carboxylic acid

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 3h;
DOI:10.1021/acs.jmedchem.1c00635

Reference yield:

: 235100-95-5
1-carbethoxy-4-cyano-4-hydroxypiperidine

: 50289-06-0
4-hydroxypiperidine-4-carboxylic acid

Guidance literature:: In sulfuric acid;

Reference yield:

: 6094-60-6
1-benzyl-4-hydroxypiperidine-4-carbonitrile

: 50289-06-0
4-hydroxypiperidine-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride; water / 0.5 h / 120 °C / microwave irradiation

2: hydrogen / palladium(II) hydroxide / ethanol / 20 h / 20 °C

With hydrogenchloride; water; hydrogen; palladium(II) hydroxide; In ethanol;