Phenol, 3-methyl-4-nitro-, labeled with carbon-14 (9CI)

Base Information

• Chemical Name: Phenol, 3-methyl-4-nitro-, labeled with carbon-14 (9CI)
• CAS No.: 910311-23-8
• Molecular Formula: C₇H₇NO₃
• Molecular Weight: 153.137
• Mol file: 910311-23-8.mol

Synonyms:Phenol, 3-methyl-4-nitro-, labeled with carbon-14 (9CI)

Chemical Property of Phenol, 3-methyl-4-nitro-, labeled with carbon-14 (9CI)

Chemical Property:

• PSA: 66.05000
• LogP: 2.13200

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phenol, 3-methyl-4-nitro-, labeled with carbon-14 (9CI)

There total 57 articles about Phenol, 3-methyl-4-nitro-, labeled with carbon-14 (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

3-methyl-phenol (108-39-4) → 3-methyl-4-nitrophenol (2581-34-2,910311-23-8)

Guidance literature:

With Vilsmeier reagent; potassium nitrate; In neat (no solvent); at 100 ℃; under 1500.15 Torr; Reagent/catalyst; Temperature; Microwave irradiation;

DOI:10.1080/15533174.2012.752395

Reference yield: 87.0%

3-methyl-phenol (108-39-4) → 2-nitro-5-methylphenol (700-38-9) + 3-methyl-4-nitrophenol (2581-34-2,910311-23-8)

Guidance literature:

With silica supported Al(NO₃)3*9H₂O; In acetone; at 20 ℃; for 0.416667h; regioselective reaction;

DOI:10.2174/1570178612666150108000402

Reference yield: 73.0%

danishefsky's diene (54125-02-9) + ((Z)-1-Nitro-prop-1-ene-2-sulfinyl)-benzene (112825-86-2) → 3-methyl-4-nitrophenol (2581-34-2,910311-23-8)

Guidance literature:

In benzene; at 25 ℃; for 24h;

DOI:10.1039/c39870000753

upstream raw materials:

3-methyl-1,4-benzoquinone 4-oxime

3-methyl-4-nitroso-phenol

4-nitro-3-methylaniline

2-methyl-4-methoxynitrosobenzene

Downstream raw materials:

C₁₃H₁₉N₂O₄PS

2-(3-Methyl-4-nitro-phenoxy)-5-trifluoromethyl-benzonitrile

C₁₄H₉ClF₃NO₃

Thiophosphoric acid O-(2-isopropoxy-ethyl) ester O'-methyl ester O''-(3-methyl-4-nitro-phenyl) ester

Refernces

• 1、 Bhooshan,Rajanna,Govardhan,Venkanna,Satish Kumar. "Kinetics and mechanism of trichloroisocyanuric acid/NaNO2-triggered nitration of aromatic compounds under acid-free and Vilsmeier-Haack conditions". . p. 445 - 462. Retrieved 2019/04/10.
• 2、 Kandpal, Neha,Dewangan, Hitesh K.,Nagwanshi, Rekha,Ghosh, Kallol K.,Satnami, Manmohan L.. "Micellar-accelerated hydrolysis of organophosphate and thiophosphates by pyridine oximate". supporting information. p. 827 - 835. Retrieved 2018/09/12.