N-tert-Butoxycarbonyl Acivicin

Base Information

Chemical Name:N-tert-Butoxycarbonyl Acivicin
CAS No.:73684-59-0
Molecular Formula:C₁₀H₁₅ClN₂O₅
Molecular Weight:278.692
Hs Code.:
Mol file:73684-59-0.mol

Synonyms:N-tert-Butoxycarbonyl Acivicin;(αS,5S)-3-Chloro-α-[[(1,1-diMethylethoxy)carbonyl]aMino]-4,5-dihydro-5-isoxazoleacetic Acid

Suppliers and Price of N-tert-Butoxycarbonyl Acivicin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-tert-ButoxycarbonylAcivicin
100mg
$ 1100.00

TRC
N-tert-ButoxycarbonylAcivicin
10mg
$ 140.00

Total 4 raw suppliers

Chemical Property of N-tert-Butoxycarbonyl Acivicin

Chemical Property:

PSA：100.71000
LogP:0.94550
Solubility.:Chloroform, Dichloromethane, DMSO, Ethyl Acetate

Purity/Quality:

99% ^*data from raw suppliers

N-tert-ButoxycarbonylAcivicin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Protected Acivicin. N-tert-Butoxycarbonyl Acivicin is related to Acivicin (CAS:42228-92-2) which is a anti tumor compound. N-tert-Butoxycarbonyl Acivicin exibits many of the same properties as Acivicin as it can go across the blood-brain barrier.

Technology Process of N-tert-Butoxycarbonyl Acivicin

There total 3 articles about N-tert-Butoxycarbonyl Acivicin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 1151863-28-3
(1R,5'S)-[1-(3-chloro-4,5-dihydroisoxazol-5-yl)-2-hydroxyethyl]carbamic acid tert-butyl ester

: 73684-59-0
tert-butyloxycarbonyl acivicin

Guidance literature:: With dipyridinium dichromate; In N,N-dimethyl-formamide; at 20 ℃; for 8h;

Reference yield:

: 1020071-17-3
(4R,5'S)-4-(3'-bromo-4',5'-dihydroisoxazol-5'-yl)-2,2-dimethyl-N-tert-butoxycarbonyloxazolidine

: 73684-59-0
tert-butyloxycarbonyl acivicin

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride / tetrahydrofuran; water / 1 h / 20 °C

2: triethylamine / dichloromethane / 16 h / 0 - 20 °C

3: dipyridinium dichromate / N,N-dimethyl-formamide / 8 h / 20 °C

With hydrogenchloride; dipyridinium dichromate; triethylamine; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide;

Reference yield:

: 1151863-27-2,1322622-94-5
(2R,5'S)-2-amino-2-(3-chloro-4,5-dihydroisoxazol-5-yl)ethanol

: 73684-59-0
tert-butyloxycarbonyl acivicin

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 16 h / 0 - 20 °C

2: dipyridinium dichromate / N,N-dimethyl-formamide / 8 h / 20 °C

With dipyridinium dichromate; triethylamine; In dichloromethane; N,N-dimethyl-formamide;