4',5-Di-O-acetyl Genistein 7-(Tri-O-acetyl-β-D-glucuronic Acid Methyl Ester)

Base Information

• Chemical Name: 4',5-Di-O-acetyl Genistein 7-(Tri-O-acetyl-β-D-glucuronic Acid Methyl Ester)
• CAS No.: 1105697-83-3
• Molecular Formula: C32H30O16
• Molecular Weight: 670.571
• Mol file: 1105697-83-3.mol

Synonyms:4',5-Di-O-acetyl Genistein 7-(Tri-O-acetyl-β-D-glucuronic Acid Methyl Ester);5-(Αcetyloxy)-3-[4-(acetyloxy)phenyl]-4-oxo-4H-1-benzopyran-7-yl β-D-Glucopyranosiduronic Αcid Μethyl Εster 2,3,4-Τriacetate

Chemical Property of 4',5-Di-O-acetyl Genistein 7-(Tri-O-acetyl-β-D-glucuronic Acid Methyl Ester)

Chemical Property:

• Melting Point: 205 °C
• Boiling Point: 748.9±60.0 °C(Predicted)
• PSA: 206.47000
• Density: 1.44±0.1 g/cm3(Predicted)
• LogP: 2.38240
• Solubility.: Dichloromethane

Purity/Quality:

4’,5-Di-O-acetylGenistein7-(Tri-O-acetyl-β-D-glucuronicAcidMethylEster) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Protected Genistein (G350000) metabolite.

Technology Process of 4',5-Di-O-acetyl Genistein 7-(Tri-O-acetyl-β-D-glucuronic Acid Methyl Ester)

There total 1 articles about 4',5-Di-O-acetyl Genistein 7-(Tri-O-acetyl-β-D-glucuronic Acid Methyl Ester) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

4-(5-acetoxy-7-hydroxy-4-oxo-4H-chromen-3-yl)phenyl acetate (23050-36-4) + C22H24F3NO11 (918158-52-8) → methyl (5,4'-di-O-acetylgenistein-7-yl β-D-2'',3'',4''-triacetylglucopyranosid)uronate (1105697-83-3)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; at 20 ℃; for 6h; Inert atmosphere; Molecular sieve;

DOI:10.1002/ejoc.200800803

Reference yield:

methyl (5,4'-di-O-acetylgenistein-7-yl β-D-2'',3'',4''-triacetylglucopyranosid)uronate (1105697-83-3) → Genistein O7-glucuronide (38482-81-4)

Guidance literature:

With water; potassium carbonate; In tetrahydrofuran; methanol; at 20 ℃; for 5h; Inert atmosphere;

DOI:10.1002/ejoc.200800803

upstream raw materials:

4-(5-acetoxy-7-hydroxy-4-oxo-4H-chromen-3-yl)phenyl acetate

C₂₂H₂₄F₃NO₁₁

Downstream raw materials:

Genistein O7-glucuronide

Refernces