3,8-Dichloro-1,5-naphthyridine

Base Information

Chemical Name:3,8-Dichloro-1,5-naphthyridine
CAS No.:28252-81-5
Molecular Formula:C₈H₄Cl₂N₂
Molecular Weight:199.039
Hs Code.:2933990090
DSSTox Substance ID:DTXSID90345891
Nikkaji Number:J99.587H
Wikidata:Q82118682
Mol file:28252-81-5.mol

Synonyms:3,8-dichloro-1,5-naphthyridine;28252-81-5;1,5-Naphthyridine, 3,8-dichloro-;SCHEMBL5598611;DTXSID90345891;3,8-Dichloro[1,5]naphthyridine #;MFCD00034435;AKOS025290158;PB28975;4,7-DICHLORO-1,5-NAPHTHYRIDINE;AS-34509;CS-0051586;A819390

Suppliers and Price of 3,8-Dichloro-1,5-naphthyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,8-Dichloro-1,5-naphthyridine
50mg
$ 175.00

SynQuest Laboratories
4,7-Dichloro-1,5-naphthyridine 95%
1 g
$ 1056.00

SynQuest Laboratories
4,7-Dichloro-1,5-naphthyridine 95%
500 mg
$ 792.00

Matrix Scientific
3,8-Dichloro-1,5-naphthyridine 95+%
1g
$ 1286.00

Crysdot
3,8-Dichloro-1,5-naphthyridine 95+%
1g
$ 750.00

Chemcia Scientific
3,8-Dichloro-[1,5]naphthyridine 95%
2.5 G
$ 960.00

Alichem
3,8-Dichloro-1,5-naphthyridine
5g
$ 2595.60

Alichem
3,8-Dichloro-1,5-naphthyridine
1g
$ 825.00

Total 9 raw suppliers

Chemical Property of 3,8-Dichloro-1,5-naphthyridine

Chemical Property:

Boiling Point:288.9±35.0 °C(Predicted)
PKA:-0.58±0.10(Predicted)
PSA：25.78000
Density:1.486±0.06 g/cm3(Predicted)
LogP:2.93660
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:197.9751535
Heavy Atom Count:12
Complexity:165

Purity/Quality:

97% ^*data from raw suppliers

3,8-Dichloro-1,5-naphthyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN=C2C=C(C=NC2=C1Cl)Cl

Technology Process of 3,8-Dichloro-1,5-naphthyridine

There total 4 articles about 3,8-Dichloro-1,5-naphthyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 27330-43-4,952059-73-3
7-chloro-4-oxo-1,4-dihydro-1,5-naphthyridine

: 28252-81-5
4,7-dichloro-1,5-naphthyridine

Guidance literature:: With N-ethyl-N,N-diisopropylamine; trichlorophosphate; In chlorobenzene; at 14 - 70 ℃; for 3h;

Reference yield:

: 22353-34-0
5-chloropyridin-3-amine

: 28252-81-5
4,7-dichloro-1,5-naphthyridine

Guidance literature:: Multi-step reaction with 3 steps

1: isopropyl alcohol / 1 h / 75 °C

2: diphenylether; biphenyl / 0.08 h / 160 - 210 °C

3: N-ethyl-N,N-diisopropylamine; trichlorophosphate / chlorobenzene / 3 h / 14 - 70 °C

With N-ethyl-N,N-diisopropylamine; trichlorophosphate; In diphenylether; biphenyl; chlorobenzene; isopropyl alcohol;

Reference yield:

: 952059-72-2
5-[(5-chloropyridin-3-ylamino)methylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione

: 28252-81-5
4,7-dichloro-1,5-naphthyridine

Guidance literature:: Multi-step reaction with 2 steps

1: diphenylether; biphenyl / 0.08 h / 160 - 210 °C

2: N-ethyl-N,N-diisopropylamine; trichlorophosphate / chlorobenzene / 3 h / 14 - 70 °C

With N-ethyl-N,N-diisopropylamine; trichlorophosphate; In diphenylether; biphenyl; chlorobenzene;